SML2243

BTSA1

≥98% (HPLC)

• Synonym(e): 3-Phenyl-1-(4-phenyl-2-thiazolyl)-1H-pyrazole-4,5-dione 4-[2-(2-thiazolyl)hydrazone]
• Empirische Formel (Hill-System): C₂₁H₁₄N₆OS₂
• CAS-Nummer: 314761-14-3
• Molekulargewicht: 430.51
• UNSPSC Code: 12352200
• NACRES: NA.77
• eCl@ss: 32150313
• Assay: ≥98% (HPLC)
• Form: powder

Eigenschaften

• assay: ≥98% (HPLC)
• form: powder
• color: red to dark red-brown
• solubility: DMSO: 2 mg/mL, clear (warmed)
• storage temp.: 2-8°C
• SMILES string: O=C1N(C2=NC(C3=CC=CC=C3)=CS2)N=C(C4=CC=CC=C4)/C1=N\NC5=NC=CS5
• InChI key: KYVZVVOQWWCVPP-HKOYGPOVSA-N

Beschreibung

Biochem/physiol Actions

BTSA1 is orally available, highly specific and potent BAX activator that binds to N-terminal activation site of Bax and induces conformational changes. BTSA1 potently induces apoptosis in leukemia cell lines and patient samples while sparing healthy cells.

orally available, highly specific and potent BAX activator that binds to N-terminal activation site of Bax

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable