SML2810

Prostetin Trifluoroacetic acid salt

≥98% (HPLC), MAP4K inhibitor, powder

• Synonym(e): 2-(4-(4-(3-(3-Chlorophenyl)-1H-pyrrolo[2,3-b]pyridin-5-yl)benzyl)piperazin-1-yl)ethan-1-ol Trifluoroacetic acid salt, 2-(4-(4-(3-(3-Chlorophenyl)-1H-pyrrolo[2,3-b]pyridin-5-yl)benzyl)piperazin-1-yl)ethanol Trifluoroacetic acid salt, 4-[[4-[3-(3-Chlorophenyl)-1H-pyrrolo[2,3-b]pyridin-5-yl]phenyl]methyl]-1-piperazineethanol Trifluoroacetic acid salt
• Empirische Formel (Hill-System): C₂₆H₂₇ClN₄O · xC₂HF₃O₂
• Molekulargewicht: 446.97 (free base basis)
• UNSPSC Code: 12352106
• NACRES: NA.77
• Assay: ≥98% (HPLC)
• Form: powder

Eigenschaften

• Produktname: Prostetin Trifluoroacetic acid salt, ≥98% (HPLC)
• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: 2-8°C

Beschreibung

Biochem/physiol Actions

Prostetin is an orally available, blood-brain barrier-penetrant, potent and metabolically stable inhibitor of the mitogen-activated protein kinase kinase kinase kinase (MAP4K, or HGK) that exhibits neuroprotective and anti-inflammatory properties. Prostetin is more potent than URMC-099 in motor neuron survival assay. Prostetin rescues CPA-induced neurodegeneration in motor neurons.

orally available, blood-brain barrier-penetrant, potent and metabolically stable inhibitor of MAP4K (HGK) that exhibits neuroprotective properties

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• Was ist los?: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable