SML2882

NRT-870-59

≥98% (HPLC)

• Synonym(e): 7-Imino-?5-?methyl-?2-?phenyl-thieno[3,?2-?c]?pyridine-?4,?6(5H,?7H)?-?dione, 7-imino-5-methyl-2-phenylthieno[3,2-c]pyridine-4,6(5H,7H)-dione
• Empirische Formel (Hill-System): C₁₄H₁₀N₂O₂S
• CAS-Nummer: 2284492-36-8
• Molekulargewicht: 270.31
• UNSPSC Code: 12352200
• NACRES: NA.77
• Assay: ≥98% (HPLC)
• Form: powder

Eigenschaften

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: N=C(C(N1C)=O)C2=C(C=C(C3=CC=CC=C3)S2)C1=O
• InChI: 1S/C14H10N2O2S/c1-16-13(17)9-7-10(8-5-3-2-4-6-8)19-12(9)11(15)14(16)18/h2-7,15H,1H3
• InChI key: IGPZTAJCUQIMOK-UHFFFAOYSA-N

Beschreibung

Biochem/physiol Actions

NRT-870-59 is a potent and selective reversible inhibitor of PTP4A3 tyrosine phosphatase that exhibits potent cytotoxicity against human ovarian and breast cancer cells grown as spheroids. NRT-870-59 does not inhibit oncogenic dual specificity phosphatase CDC25B.

potent and selective reversible inhibitor of PTP4A3 tyrosine phosphatase

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• Was ist los?: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable