SML2980

G6PDi-1

≥98% (HPLC), G6PD inhibitor, powder

• Synonym(e): 4-([5-oxo-6H,7H,8H,9H-cyclohepta[d]pyrimidin-2-yl]amino)thiophene-2-carbonitrile
• Empirische Formel (Hill-System): C₁₄H₁₂N₄OS
• CAS-Nummer: 2457232-14-1
• Molekulargewicht: 284.34
• UNSPSC Code: 12352200
• NACRES: NA.77
• MDL number: MFCD32899271
• Assay: ≥98% (HPLC)
• Form: powder

Eigenschaften

• Produktname: G6PDi-1, ≥98% (HPLC)
• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: N#CC1=CC(NC2=NC=C3C(CCCCC3=N2)=O)=CS1
• InChI: 1S/C14H12N4OS/c15-6-10-5-9(8-20-10)17-14-16-7-11-12(18-14)3-1-2-4-13(11)19/h5,7-8H,1-4H2,(H,16,17,18)
• InChI key: USWCHVCZOGGQQA-UHFFFAOYSA-N

Beschreibung

Biochem/physiol Actions

G6PDi-1 is a cell penetrant potent and selective nonsteroidal inhibitor of glucose-6-phosphate dehydrogenase (G6PD). G6PDi-1 strongly depletes NADPH in lymphocytes. It decreases inflammatory cytokine response in macrophages, and suppresses respiratory burst in neutrophils.

cell penetrant potent and selective nonsteroidal inhibitor of glucose-6-phosphate dehydrogenase (G6PD)

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• Was ist los?: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable