SML3079

Ponalrestat

≥98% (HPLC)

• Synonym(e): 3-[(4-Bromo-2-fluorophenyl)methyl]-3,4-dihydro-4-oxo-1-phthalazineacetic acid, ICI 128436, MK538
• Empirische Formel (Hill-System): C₁₇H₁₂BrFN₂O₃
• CAS-Nummer: 72702-95-5
• Molekulargewicht: 391.19
• UNSPSC Code: 12352200
• NACRES: NA.77
• MDL number: MFCD00204117
• Assay: ≥98% (HPLC)
• Form: powder

Eigenschaften

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: OC(CC(C1=CC=CC=C1C2=O)=NN2CC3=CC=C(C=C3F)Br)=O
• InChI: 1S/C17H12BrFN2O3/c18-11-6-5-10(14(19)7-11)9-21-17(24)13-4-2-1-3-12(13)15(20-21)8-16(22)23/h1-7H,8-9H2,(H,22,23)
• InChI key: LKBFFDOJUKLQNY-UHFFFAOYSA-N

Beschreibung

Biochem/physiol Actions

Ponalrestat is an orally available, potent and specific inhibitor of aldehyde reductase 2 (ALR2) that blocks the conversion of glucose to sorbitol. Ponalrestat promotes root elongation through the inhibition of the flavin monooxygenase YUCCA in Arabidopsis.

orally available, potent and specific inhibitor of aldehyde reductase 2 (ALR2)

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• Was ist los?: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable