SML3091

Irresistin-16

≥98% (HPLC)

• Synonym(e): 7H-Pyrrolo[3,2-f]quinazoline-1,3-diamine,7-([1,1?-biphenyl]-4-ylmethyl), IRS-16
• Empirische Formel (Hill-System): C₂₃H₁₉N₅
• CAS-Nummer: 2624247-60-3
• Molekulargewicht: 365.43
• UNSPSC Code: 51111800
• NACRES: NA.77
• Assay: ≥98% (HPLC)
• Form: powder

Eigenschaften

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: NC1=NC(N)=NC2=C1C3=C(C=C2)N(CC4=CC=C(C=C4)C5=CC=CC=C5)C=C3
• InChI: 1S/C23H19N5/c24-22-21-18-12-13-28(20(18)11-10-19(21)26-23(25)27-22)14-15-6-8-17(9-7-15)16-4-2-1-3-5-16/h1-13H,14H2,(H4,24,25,26,27)
• InChI key: CKQXMSDRDDHCOR-UHFFFAOYSA-N

Beschreibung

Biochem/physiol Actions

Irresistin-16, an SCH 79797 derivative, is a broad spectrum bactericidal antibiotic that is effective in both gram-positive and gram-negative bacteria and exhibits low frequency of resistance. Irresistin-16 act through interruption of bacterial folate metabolism and bacterial membrane integrity. It inhibits E. coli dihydrofolate reductase FolA. Irresistin-16 is effective in mouse gonorrhea infection model.

broad spectrum bactericidal antibiotic that is effective in both gram-positive and gram-negative bacteria

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• Was ist los?: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable