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The solubility of this product has not been tested by QC, and there is no solubility information available in our database or COA. However, according to a Google search, the solubility of Ac2-26 trifluoroacetate is as follows:
In Vitro:
- H2O: 0.11 mg/mL (0.03 mM; ultrasonic and adjust pH to 13 with NaOH)
- DMSO: < 1 mg/mL (ultrasonic) (insoluble or slightly soluble)
In Vivo:
- Solvent 1: PBS
- Solubility: 1 mg/mL (0.31 mM)
- Clarity: Clear solution
- Requirements: Ultrasonic and adjust pH to 9 with NaOH
Fortfahren mit
SML3198
Ac2-26 trifluoroacetate
≥98% (HPLC)
Synonym(e):
Ac2-26 TFA, LC1 trifluoroacetate, Lipocortin 1- trifluoroacetate, Ac-Ala-Met-Val-Ser-Glu-Phe-Leu-Lys-Gln-Ala-Trp-Phe-Ile-Glu-Asn-Glu-Glu-Gln-Glu-Tyr-Val-Gln-Thr-Val-Lys-OH trifluoroacetate, Annexin A1 trifluoroacetate, AnxA1 trifluoroacetate
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| Größe/SKU | Verfügbarkeit | Preis |
|---|---|---|
1 mg | Warenkorb auf Verfügbarkeit prüfen | € 86,60 |
Über diesen Artikel
Empirische Formel (Hill-System):
C141H210N32O44S
Molekulargewicht:
3089.43
NACRES:
NA.77
UNSPSC Code:
12352107
Assay:
≥98% (HPLC)
Form:
powder
Technischer Dienst
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Unterstützung erhaltenGeneral description
Ac2-26 is a Lipocortin 1/Annexin 1 Peptide Mimetic, derived from the N-terminal region of annexin A1 (AnxA1). It contains residues 2–26 of AnxA1. Ac2-26 activates formyl peptide receptor family members formyl peptide receptor (FPR), FPR-like (FPRL) 1 and FPRL2. It exhibits an anti-inflammatory effect by inhibiting the adhesion and transmigration of leukocytes (leukocyte extravasation). This facilitates the growth and migration of epithelial cells, aiding in tissue repair. Ac2-26 also serves as a cardioprotective peptide. It is observed that Ac2-26 reduces acute lung injury caused by ischemia and reperfusion.
Biochem/physiol Actions
Lipocortin 1/Annexin 1 Peptide Mimetic; activates formyl peptide receptor family
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Dieser Artikel | |||
|---|---|---|---|
| description ≥98% (HPLC) | description ≥97% (HPLC) | description ≥95% (HPLC) | description ≥97% (HPLC) |
| form powder | form powder | form lyophilized powder | form powder |
| assay ≥98% (HPLC) | assay ≥97% (HPLC) | assay ≥95% (HPLC) | assay ≥97% (HPLC) |
| Quality Level 100 | Quality Level 200 | Quality Level 100 | Quality Level 200 |
| storage temp. −20°C | storage temp. −20°C | storage temp. −20°C | storage temp. −20°C |
| color white to off-white | color - | color white to beige | color - |
Lagerklasse
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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What is the solubility of the product SML3198, Ac2-26 trifluoroacetate?
1 answer-
Helpful?
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Ac2-26 trifluoroacetate ≥98% (HPLC) (sigmaaldrich.com) 上記を購入したのですが、溶かす溶媒は蒸留水で良いのでしょうか？またストックする濃度についても教えてください。
1 answer-
The solubility of this product is not determined. However, other sources suggest that this compound is soluble in Phosphate Buffered Saline at 1 mg/mL. Sonication or increasing the pH to 9 by adding NaOH drop-wise may be required.
Helpful?
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