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Über diesen Artikel
Empirische Formel (Hill-System):
C30H18O10
CAS-Nummer:
Molekulargewicht:
538.46
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
Assay:
≥97% (HPLC)
Form:
powder
Storage condition:
desiccated
Preise und Verfügbarkeit sind derzeit nicht verfügbar.
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Unterstützung erhaltenQuality Segment
assay
≥97% (HPLC)
form
powder
storage condition
desiccated
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
-10 to -25°C
SMILES string
[o]1c2c([c](cc1c6ccc(cc6)O)=O)c(c(c(c2)O)Oc3ccc(cc3)c4[o]c5c([c](c4)=O)c(cc(c5)O)O)O
InChI
1S/C30H18O10/c31-16-5-1-14(2-6-16)24-12-21(35)28-26(40-24)13-22(36)30(29(28)37)38-18-7-3-15(4-8-18)23-11-20(34)27-19(33)9-17(32)10-25(27)39-23/h1-13,31-33,36-37H
InChI key
WTDHMFBJQJSTMH-UHFFFAOYSA-N
Biochem/physiol Actions
Hinokiflavone is a plant biflavone that exhibit potent anticancer, hepatoprotective, antibacterial, antiviral, and anti-inflammatory activities. Hinokiflavone induces apoptosis and cell cycle arrest, and blocks migration and invasion of melanoma cells. It is a potent inhibitor of dengue 2 virus RNA-dependent RNA polymerase (DV-NS5 RdRp). Hinokiflavone is a modulator of pre-mRNA splicing in cells. It increases SUMOylation of a subset of spliceosome proteins by inhibiting SENP1 protease activity. It induces apoptosis in esophageal squamous cell carcinoma (ESCC) through regulation of PI3K/AKT/mTOR pathway.
Modulator of pre-mRNA splicing in cells; potent inhibitor of dengue 2 virus RNA-dependent RNA polymerase (DV-NS5 RdRp)
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Dieser Artikel | |||
|---|---|---|---|
| description ≥97% (HPLC) | description analytical standard | description ≥98% (HPLC) | description ≥99.0% |
| form powder | form - | form powder | form powder |
| assay ≥97% (HPLC) | assay ≥99.0% (HPLC) | assay ≥98% (HPLC) | assay ≥99.0% |
| Quality Level 100 | Quality Level 100 | Quality Level - | Quality Level 200 |
| storage temp. -10 to -25°C | storage temp. - | storage temp. 2-8°C | storage temp. - |
| solubility DMSO: 2 mg/mL, clear | solubility - | solubility DMSO: 2 mg/mL, clear | solubility - |
| storage condition desiccated | storage condition - | storage condition - | storage condition - |
Lagerklasse
11 - Combustible Solids
WGK
WGK 3
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
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