SML3464

Gossypetin

≥98% (HPLC), MKK3 and MKK6 protein kinases inhibitor, powder

• Synonym(e): 2-(3,4-Dihydroxyphenyl)-3,5,7,8-tetrahydroxy-4H-1-benzopyran-4-one, 8-Hydroxyquercetin, Articulatidin, Equisporol
• Empirische Formel (Hill-System): C₁₅H₁₀O₈
• CAS-Nummer: 489-35-0
• Molekulargewicht: 318.24
• NACRES: NA.77
• UNSPSC Code: 12352200
• MDL number: MFCD00017680
• Assay: ≥98% (HPLC)
• Form: powder

Eigenschaften

• Produktname: Gossypetin, ≥98% (HPLC)
• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: , light green to yellow
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: -10 to -25°C
• SMILES string: OC1=CC(O)=C2C(C(O)=C(OC2=C1O)C3=CC=C(C(O)=C3)O)=O
• InChI: 1S/C15H10O8/c16-6-2-1-5(3-7(6)17)14-13(22)12(21)10-8(18)4-9(19)11(20)15(10)23-14/h1-4,16-20,22H
• InChI key: YRRAGUMVDQQZIY-UHFFFAOYSA-N

Beschreibung

Biochem/physiol Actions

Antioxidant, antibacterial, anticancer; potent inhibitor of MKK3 and MKK6 protein kinases

Gossypetin is a hexahydroxylated flavonoid found in the flowers and the calyx of Hibiscus, which exhibits numerous pharmacological effects, including antioxidant, antibacterial and anticancer activities. It induces apoptosis and autophagic cell death in prostate cancer cells. Gossypetin is a potent inhibitor of MKK3 and MKK6 protein kinases that suppresses esophageal cancer growth.

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• Was ist los?: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable