SML3570

M4K2234NC

≥98% (HPLC)

• Synonym(e): (2-Fluoro-4-(5-(4-(4-isopropylpiperazin-1-yl)phenyl)-4-methylpyridin-3-yl)-6-methoxyphenyl)(pyrrolidin-1-yl), M4K2234 inactive control, M4K2234 negative control
• Empirische Formel (Hill-System): C₃₁H₃₇FN₄O₂
• Molekulargewicht: 516.65
• UNSPSC Code: 12352200
• NACRES: NA.77
• Assay: ≥98% (HPLC)
• Form: powder

Eigenschaften

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear (Warmed)
• storage temp.: 2-8°C
• SMILES string: CC(C)N1CCN(CC1)C2=CC=C(C3=C(C)C(C4=CC(OC)=C(C(N5CCCC5)=O)C(F)=C4)=CN=C3)C=C2
• InChI key: WFJOMSKCDAOJBT-UHFFFAOYSA-N

Beschreibung

Biochem/physiol Actions

Inactive analog of and negative control for the potent and selective TGF-β type I receptors ALK1/ACVRL1 & ALK2/ACVR1 inhibitor M4K2234.

M4K2234NC is an inactive analog of and the recommended negative control for the potent and selective TGF-β type I receptors ALK1/ACVRL1 & ALK2/ACVR1 inhibitor M4K2234 (ALK1/2 IC50 >10 μM/ 5.69 μM by cellular NanoBRET assays; IC50 = 83 nM/13 nM using M4K2234).

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• Was ist los?: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable