SML3789

MS67

≥98% (HPLC)

• Synonym(e): N-(2′-fluoro-5′-((2-(((S)-1-((2S,4R)-4-hydroxy-2-(((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)carbamoyl)pyrrolidin-1-yl)-3,3dimethyl-1-oxobutan-2-yl)amino)-2-oxoethyl)carbamoyl)-4-((3S,5R)-3,4,5-trimethylpiperazin-1-yl)-[1,1′-biphenyl]-3-yl)-6-oxo 4-(trifluoromethyl)-1,6-dihydropyridine-3-carboxamide
• Empirische Formel (Hill-System): C₅₂H₅₉F₄N₉O₇S
• CAS-Nummer: 2407452-77-9
• Molekulargewicht: 1030.14
• NACRES: NA.21
• UNSPSC Code: 12352200
• Assay: ≥98% (HPLC)
• Form: powder

Eigenschaften

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: -10 to -25°C

Beschreibung

Biochem/physiol Actions

Cell penetrant, potent and selective WD40 repeat domain protein 5 (WDR5) degrader

MS67 is a cell penetrant, potent and selective WD40 repeat domain protein 5 (WDR5) degrader that effectively and selectively degrades WDR5 in human MLL-r AML and PDAC cells.

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• Was ist los?: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable