SML3876

SHM115

≥98% (HPLC)

• Synonym(e): 6-((Perfluorophenyl)amino)-[1,2,5]oxadiazolo[3,4-b]pyridin-5-ol, 6-[(2,3,4,5,6-Pentafluorophenyl)amino]-[1,2,5]oxadiazolo[3,4-b]pyridin-5(3H)-one
• Empirische Formel (Hill-System): C₁₁H₃F₅N₄O₂
• CAS-Nummer: 2918770-46-2
• Molekulargewicht: 318.16
• NACRES: NA.28
• UNSPSC Code: 12352203
• Assay: ≥98% (HPLC)
• Form: powder

Eigenschaften

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: OC1=NC2=NON=C2C=C1NC3=C(C(F)=C(C(F)=C3F)F)F

Beschreibung

Biochem/physiol Actions

Orally active mitochondria uncoupler that increases the energy expenditure and lowers the body fat mass in vivo.
SHM115 is an orally active mitochondria uncoupler (EC50 = 17 μM; measured as oxygen consumption rate (OCR) increase in L6 rat myoblast cells) that increases the energy expenditure and lowers the body fat mass in two diet-induced obesity mouse models, including an obesity prevention model (130 mg/kg/d via chow) and an obesity reversal model (130 mg/kg/d via oral gavage).

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• Was ist los?: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable