SML3901

Crenolanib trifluoroacetate

≥98% (HPLC)

• Synonym(e): 1-[2-[5-[(3-Methyloxetan-3-yl)methoxy]benzimidazol-1-yl]quinolin-8-yl]piperidin-4-amine trifluoroacetate, 1-[2-[5-[(3-methyl-3-oxetanyl)methoxy]-1H-benzimidazol-1-yl]-8-quinolinyl]-4-piperidinamine trifluoroacetate, ARO 00 trifluoroacetate2, CP 868596 trifluoroacetate, CP868596 trifluoroacetate
• Empirische Formel (Hill-System): C₂₆H₂₉N₅O₂ · xC₂HF₃O₂
• Molekulargewicht: 443.54 (free base basis)
• UNSPSC Code: 12352200
• NACRES: NA.21
• MDL number: MFCD21609260
• Assay: ≥98% (HPLC)
• Form: powder
• Storage condition: desiccated

Eigenschaften

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• storage condition: desiccated
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: -10 to -25°C
• SMILES string: N6(CCC(CC6)N)c1c2nc(ccc2ccc1)[n]3c4c(nc3)cc(cc4)OCC5(COC5)C
• InChI: 1S/C26H29N5O2/c1-26(14-32-15-26)16-33-20-6-7-22-21(13-20)28-17-31(22)24-8-5-18-3-2-4-23(25(18)29-24)30-11-9-19(27)10-12-30/h2-8,13,17,19H,9-12,14-16,27H2,1H3
• InChI key: DYNHJHQFHQTFTP-UHFFFAOYSA-N

Beschreibung

Biochem/physiol Actions

Crenolanib is an orally bioavailable, potent and selective platelet-derived growth factor receptor (PDGFR) tyrosine kinase inhibitor. Also crenolanib potently inhibits FLT3.

Platelet-derived growth factor receptor (PDGFR) tyrosine kinase inhibitor

Disclaimer

Hygroscopic

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• Was ist los?: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable