SML4020

XQ2B

≥95% (HPLC)

• Synonym(e): Cyclo(D-Phe-Ala-Thr-Arg-Leu-D-Phe-Pro-Val-Arg-Leu)
• Empirische Formel (Hill-System): C₅₉H₉₂N₁₆O₁₁
• CAS-Nummer: 2104728-28-9
• Molekulargewicht: 1201.46
• NACRES: NA.21
• UNSPSC Code: 12352200
• Assay: ≥95% (HPLC)
• Form: (Powder or Lyophilized powder or film)

Eigenschaften

• Quality Segment: 100
• assay: ≥95% (HPLC)
• form: (Powder or Lyophilized powder or film)
• color: white to off-white
• storage temp.: -10 to -25°C
• SMILES string: O=C([C@H]1N(C([C@H](NC([C@H](CC(C)C)NC([C@H](CCCNC(N)=N)NC([C@@H](N2)[C@H](C)O)=O)=O)=O)CC3=CC=CC=C3)=O)CCC1)N[C@H](C(N[C@H](C(N[C@@H](CC(C)C)C(N[C@H](CC4=CC=CC=C4)C(N[C@H](C2=O)C)=O)=O)=O)CCCNC(N)=N)=O)C(C)C

Beschreibung

Biochem/physiol Actions

In vivo active specific cyclic GMP-AMP synthase (cGAS) inhibitor that binds to DNA binding site of cGAS.
XQ2B, macrocyclic peptide derived from Gramicidin S, acts a specific cyclic GMP-AMP synthase (cGAS) inhibitor by directly targeting protein-DNA interface. XQ2B attenuates the host innate antiviral response.

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable