SML4029

NVS-STG2

≥98% (HPLC)

• Synonym(e): Methyl 4-((4-(2-(tert-butyl)-5,5-dimethyl-1,3-dioxan-2-yl)benzyl)amino)-3-methoxybenzoate
• Empirische Formel (Hill-System): C₂₅H₃₃NO₅
• CAS-Nummer: 3030588-01-0
• Molekulargewicht: 427.53
• NACRES: NA.21
• UNSPSC Code: 12352200
• Assay: ≥98% (HPLC)
• Form: powder

Eigenschaften

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: OC(C1=CC=C(NCC2=CC=C(C3(C(C)(C)C)OCC(C)(C)CO3)C=C2)C(OC)=C1)=O
• InChI key: CZSPKEVHLRWAFC-UHFFFAOYSA-N

Beschreibung

Biochem/physiol Actions

Potent STING allosteric agonist that induces a STING-mediated immune responses in cells.

NVS-STG2 is a potent STING (stimulator of interferon genes) allosteric agonist (AC=5.2 µM) that induces a STING-mediated immune responses in cells. It elicits potent antitumor activity in animal models. NVS-STG2 acts as molecular glue that binds the transmembrane domains of the neighboring STING dimers.

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• Was ist los?: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable