SML4047

MitoTEMPOL

≥97% (HPLC)

• Synonym(e): 2,2,6,6-Tetramethyl-4-[[5-(triphenylphosphonio)pentyl]oxy]-1-piperidinyloxy bromide, 2,2,6,6-Tetramethyl-4-[5-(triphenylphosphonio)pentoxy]piperidin-1-oxybromide, Mito-TEMPOL
• Empirische Formel (Hill-System): C₃₂H₄₂NO₂P· Br
• CAS-Nummer: 1101113-39-6
• Molekulargewicht: 583.56
• UNSPSC Code: 12352200
• Assay: ≥97% (HPLC)
• Form: (Solid or Waxy semi-solid)

Eigenschaften

• Quality Segment: 100
• assay: ≥97% (HPLC)
• form: (Solid or Waxy semi-solid)
• color: white to light orange
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: -10 to -25°C

Beschreibung

Biochem/physiol Actions

MitoTEMPOL is a mitochondria-targeting antioxidant composed of the piperidine nitroxide TEMPOL and the lipophilic triphenylphosphonium cation. MitoTEMPOL is more active toward ubiquinol in mitochondrial membranes than butylTEMPOL, TEMPO and TEMPOL. Systemic administration of mitotempol prevents the sustained elevations of blood pressure in rats exposed to intermittent hypoxia (IH) for 10 days (10 mg/kg, i.p.).

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• Was ist los?: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable