SML4150

Ciprofloxacin hydrochloride hydrate

≥98% (HPLC), powder

• Synonym(e): 1-Cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid hydrochloride hydrate, 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid monohydrochloride, monohydrate
• Empirische Formel (Hill-System): C₁₇H₁₈FN₃O₃·HCl · xH₂O
• CAS-Nummer: 128074-72-6
• Molekulargewicht: 367.80 (anhydrous basis)
• MDL number: MFCD00079044
• NACRES: NA.21
• Assay: ≥98% (HPLC)
• Form: powder
• Storage condition: desiccated

Eigenschaften

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• storage condition: desiccated
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: -10 to -25°C
• SMILES string: O=C(C1=CN(C2CC2)C3=CC(N4CCNCC4)=C(C=C3C1=O)F)O.Cl.[xH2O]

Beschreibung

Application

Ciprofloxacin hydrochloride hydrate is suitable for use in research to study antibiotic resistance mechanisms. It is also used to inhibit cell proliferation and to sensitize cells to TRAIL (TNF-related apoptosis-inducing ligand) -Induced apotosis.

Biochem/physiol Actions

Ciprofloxacinis a fluoroquinolone antibiotic with broad-spectrum activity, which killsbacteria by blocking DNA gyrase and type IV topoisomerase—critical enzymes forDNA replication and transcription—leading to cell death. It is effectiveagainst a broad array of both Gram-positive and Gram-negative bacteria, inaddition to Mycoplasmas. While the hydrochloride form of ciprofloxacin ishighly soluble in water, ciprofloxacin itself is only sparingly soluble inaqueous solutions.

Disclaimer

Hygroscopic Store with desiccant

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• Was ist los?: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable