U115

U-101958 maleate salt

solid

• Synonym(e): 1-Benzyl-4-aminomethyl-N-[(3′-isopropoxy)-2′-pyridyl]piperidine maleate salt
• Empirische Formel (Hill-System): C₂₁H₂₉N₃O · C₄H₄O₄
• CAS-Nummer: 224170-09-6
• Molekulargewicht: 455.55
• NACRES: NA.77
• PubChem Substance ID: 24277945
• UNSPSC Code: 12352200
• MDL number: MFCD01529984
• Form: solid

Eigenschaften

• form: solid
• color: off-white
• solubility: DMSO: 11 mg/mL, ethanol: 2.7 mg/mL, H₂O: 3 mg/mL
• SMILES string: OC(=O)\C=C/C(O)=O.CC(C)Oc1cccnc1N(C)C2CCN(CC2)Cc3ccccc3
• InChI: 1S/C21H29N3O.C4H4O4/c1-17(2)25-20-10-7-13-22-21(20)23(3)19-11-14-24(15-12-19)16-18-8-5-4-6-9-18;5-3(6)1-2-4(7)8/h4-10,13,17,19H,11-12,14-16H2,1-3H3;1-2H,(H,5,6)(H,7,8)/b;2-1-
• InChI key: KPYPLDPMBWPEBO-BTJKTKAUSA-N
• Gene Information: human ... DRD4(1815)

Beschreibung

Biochem/physiol Actions

U-101958 maleate salt is a selective D₄ dopamine receptor antagonist. Studies have reported that U-101958 maleate cannot inhibit bromocriptine-mediated [³H]thymidine incorporation in opossum kidney (OK) cells.

Preparation Note

U-101958 maleate salt is soluble in water (at 3 mg/mL), ethanol (2.7 mg/mL), and DMSO (11 mg/mL).

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• Was ist los?: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• PSA (Persönliche Schutzausrüstung): Eyeshields, Gloves, type N95 (US)