Fortfahren mit
W4262
1400W dihydrochloride
>98%, potent and selective iNOS inhibitor , solid
Synonym(e):
N-([3-(Aminomethyl)phenyl]methyl)ethanimidamide dihydrochloride
Größe auswählen
| Größe/SKU | Verfügbarkeit | Preis |
|---|---|---|
10 mg | Warenkorb auf Verfügbarkeit prüfen | € 164,00 |
Über diesen Artikel
Produktname
1400W dihydrochloride, >98%, solid
Quality Segment
assay
>98%
form
solid
storage condition
desiccated
originator
GlaxoSmithKline
shipped in
wet ice
storage temp.
−20°C
SMILES string
Cl[H].Cl[H].CC(=N)NCc1cccc(CN)c1
InChI
1S/C10H15N3.2ClH/c1-8(12)13-7-10-4-2-3-9(5-10)6-11;;/h2-5H,6-7,11H2,1H3,(H2,12,13);2*1H
InChI key
WDJHSQZCZGPGAA-UHFFFAOYSA-N
Gene Information
human ... NOS1(4842), NOS2(4843), NOS3(4846)
Application
- as a strong inhibitor of inducible nitric oxide to analyse its effect on intestinal ischemia/reperfusion (I/R) injury model in rat
- as inducible nitric oxide synthase (iNOS)-selective inhibitor, to elucidate the mechanism of PM10-induced endothelial dysfunction
- to study its efficacy on renal ischemia/ reperfusion injury in rats
- as iNOS inhibitor to investigate its ability to counteract spatial memory deficits after hypobaric hypoxia reoxygenation
Biochem/physiol Actions
Features and Benefits
1 of 1
Dieser Artikel | |||
|---|---|---|---|
| description >98%, solid | description ≥98% (HPLC) | description ≥98% (HPLC) | description A selective, cell-permeable, irreversible, slow, tight-binding inhibitor of inducible nitric oxide synthase (iNOS; Kd = 7 nM). |
| assay >98% | assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay ≥95% (HPLC) |
| form solid | form lyophilized solid | form powder | form solid |
| Quality Level 100 | Quality Level 100 | Quality Level 100 | Quality Level 100 |
| storage temp. −20°C | storage temp. −20°C | storage temp. 2-8°C | storage temp. −20°C |
| storage condition desiccated | storage condition desiccated | storage condition desiccated | storage condition desiccated (hygroscopic), OK to freeze |
| originator GlaxoSmithKline | originator - | originator - | originator - |
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Lagerklasse
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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