- Phenolics from Caesalpinia ferrea Mart.: antioxidant, cytotoxic and hypolipidemic activity.
Phenolics from Caesalpinia ferrea Mart.: antioxidant, cytotoxic and hypolipidemic activity.
Die Pharmazie (2015-09-19)
M A Nawwar, S A Hussein, A M El-Mousallami, A N Hashim, M A Mousa, M H Hetta, M A Hamed, V Werner, A Becker, B Haertel, U Lindequist
PMID26380526
ZUSAMMENFASSUNG
Nine phenolics were isolated from the aqueous ethanol extract of the leaves of Caesalpinia ferrea. The isolates were characterized for the first time from that plant. The structures of all isolates (1-9) were elucidated by conventional methods, spectroscopic analysis, including 1 D and 2D NMR, and by HR-ESIMS as well. The antioxidant capacities using the ORAC method and the cytotoxic activity using the neutral red assay (NRU) for that extract and three major isolates have been evaluated. In addition, the hypolipidemic activity (in vitro and in vivo) of the extract has been assessed.
MATERIALIEN
Produktnummer
Marke
Produktbeschreibung
Sigma-Aldrich
Neutralrot-Lösung (0,33 %), 3.3 g/L in DPBS, sterile-filtered, BioReagent, suitable for cell culture
Sigma-Aldrich
SyntheChol® NS0-Supplement, 500 ×, synthetic cholesterol, animal component-free, sterile-filtered, aqueous solution, suitable for cell culture