T5428

Tetramethylrhodamine methyl ester perchlorate

≥95% purity, powder

• Synonym(s): TMRM
• Linear Formula: C₂₅H₂₅N₂O₃ · ClO₄
• CAS Number: 115532-50-8
• Molecular Weight: 500.93
• Beilstein: 7162165
• MDL number: MFCD00274460
• UNSPSC Code: 12171500
• PubChem Substance ID: 24900280
• NACRES: NA.47

Properties

• Product Name: Tetramethylrhodamine methyl ester perchlorate, ≥95%
• Quality Level: 200
• Assay: ≥95%
• form: powder
• composition: Carbon: 57.5-62.4%; ; Nitrogen: 5.3-5.9%
• technique(s): titration: suitable
• color: dark green
• solubility: methanol: 5 mg/mL, clear
• εmax: >95000 at 546-552 nm in methanol
• fluorescence: λ_em 573 nm in methanol
• application(s): diagnostic assay manufacturing; hematology; histology
• storage temp.: 2-8°C
• SMILES string: [O-]Cl(=O)(=O)=O.COC(=O)c1ccccc1C2=C3C=C\C(C=C3Oc4cc(ccc24)N(C)C)=[N+](\C)C
• InChI: 1S/C25H25N2O3.ClHO4/c1-26(2)16-10-12-20-22(14-16)30-23-15-17(27(3)4)11-13-21(23)24(20)18-8-6-7-9-19(18)25(28)29-5;2-1(3,4)5/h6-15H,1-5H3;(H,2,3,4,5)/q+1;/p-1
• InChI key: PFYWPQMAWCYNGW-UHFFFAOYSA-M

Description

General description

Tetramethylrhodamine methyl ester perchlorate (TMRM) is a membrane-permeant, cationic, fluorescent dye that can label mitochondria and mark embryonic stem cell/induced pluripotent stem cell-derived cardiomyocytes. It is useful for the isolation of mature cardiomyocytes.[1]

Application

Tetramethylrhodamine methyl ester perchlorate (TMRM) has been used as a sensitive probe for the detection of mitochondrial membrane potential.[2][3]

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves