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EMU060481

MISSION® esiRNA

targeting mouse Flt3

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€212.00

50 μG

€382.00

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About This Item

UNSPSC Code:
41105324
NACRES:
NA.51

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description

Powered by Eupheria Biotech

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

CCCACAGGGAAAGCTGTAAAGAAGAAGGCCCTGCTGTTGTCAGAAAGGAGGAAAAGGTACTTCATGAGTTGTTCGGAACAGACATCAGATGCTGTGCTAGAAATGCACTGGGCCGCGAATGCACCAAGCTGTTCACCATAGATCTAAACCAGGCTCCTCAGAGCACACTGCCCCAGTTATTCCTGAAAGTGGGGGAACCCTTGTGGATCAGGTGTAAGGCCATCCATGTGAACCATGGATTCGGGCTCACCTGGGAGCTGGAAGACAAAGCCCTGGAGGAGGGCAGCTACTTTGAGATGAGTACCTACTCCACAAACAGGACCATGATTCGGATTCTCTTGGCCTTTGTGTCTTCCGTGGGAAGGAACGACACCGGATATTACACCTGCTCTTCCTCAAAGC

Ensembl | mouse accession no.

ENSMUSG00000042817

NCBI accession no.

NM_010229

shipped in

ambient

storage temp.

−20°C

Gene Information

mouse ... FLT3(14255), Flt3(14255)

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MISSION® esiRNA targeting mouse Flt3

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MISSION® esiRNA targeting mouse Flot1

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EMU002671

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MISSION® esiRNA targeting mouse Flot2

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EMU009561

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MISSION® esiRNA targeting mouse Flrt3

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EMU154761

MISSION® esiRNA

product line

MISSION®

product line

MISSION®

product line

MISSION®

product line

MISSION®

Ensembl | mouse accession no.

ENSMUSG00000042817

Ensembl | mouse accession no.

ENSMUSG00000059714

Ensembl | mouse accession no.

ENSMUSG00000061981

Ensembl | mouse accession no.

ENSMUSG00000051379

Gene Information

mouse ... FLT3(14255), Flt3(14255)

Gene Information

mouse ... FLOT1(14251), Flot1(14251)

Gene Information

mouse ... FLOT2(14252), Flot2(14252)

Gene Information

mouse ... FLRT3(71436), Flrt3(71436)

esiRNA cDNA target sequence

CCCACAGGGAAAGCTGTAAAGAAGAAGGCCCTGCTGTTGTCAGAAAGGAGGAAAAGGTACTTCATGAGTTGTTCGGAACAGACATCAGATGCTGTGCTAGAAATGCACTGGGCCGCGAATGCACCAAGCTGTTCACCATAGATCTAAACCAGGCTCCTCAGAGCACACTGCCCCAGTTATTCCTGAAAGTGGGGGAACCCTTGTGGATCAGGTGTAAGGCCATCCATGTGAACCATGGATTCGGGCTCACCTGGGAGCTGGAAGACAAAGCCCTGGAGGAGGGCAGCTACTTTGAGATGAGTACCTACTCCACAAACAGGACCATGATTCGGATTCTCTTGGCCTTTGTGTCTTCCGTGGGAAGGAACGACACCGGATATTACACCTGCTCTTCCTCAAAGC

esiRNA cDNA target sequence

TGCATTCAGCAAATCCAGAGGATCTCTCTCAACACACTGACCCTCAATGTCAAGAGTGAAAAGGTTTATACCCGCCACGGGGTCCCCATCTCAGTCACGGGCATTGCCCAGGTGAAAATCCAGGGCCAGAACAAGGAGATGCTGGCAGCTGCCTGCCAGATGTTCCTGGGGAAGACAGAGGCGGAGATTGCCCACATTGCCCTGGAGACACTGGAAGGCCACCAGAGGGCAATCATGGCCCACATGACTGTGGAGGAGATCTATAAGGATAGACAGAAATTCTCAGAGCAGGTTTTCAAAGTGGCCTCCTCCGACCTGGTCAACATGGGTATCAGCGTGGTTAGCTACACTTTGAAGGATATTCATGATGACCAGGATTACTTACACTCGTTAGGAAAGGCTCG

esiRNA cDNA target sequence

AGTTCCTGGGCAAGAACGTACAGGACATTAAGAACGTCGTGCTGCAGACCCTGGAGGGGCATCTACGCTCTATCCTAGGGACTCTGACTGTAGAACAGATTTATCAGGACCGAGACCAGTTTGCCAAGCTGGTGCGGGAAGTGGCGGCCCCCGATGTTGGCCGCATGGGCATCGAGATCCTCAGCTTCACCATCAAGGATGTTTATGACAAAGTAGACTATCTGAGCTCCCTGGGCAAGACACAGACTGCTGTGGTGCAGAGAGATGCAGACATTGGTGTGGCAGAGGCAGAACGGGACGCAGGCATCCGGGAAGCTGAATGCAAGAAGGAGATGCTAGATGTGAAGTTCATGGCAGACACCAAGATCGCTGACTCTAAGAGAGCCTTTGAGCTTCAAAAGTCAGCCTTCAGCGAG

esiRNA cDNA target sequence

CACTCTACCTTCAGAACAACCAAATAAACAATGTTGGGATTCCTTCCGATTTGAAGAACTTGCTGAAAGTACAAAGAATATACCTATACCACAACAGTTTAGATGAATTCCCTACCAACCTTCCAAAGTATGTCAAAGAGTTACATTTGCAAGAGAATAACATAAGGACTATCACCTATGATTCACTTTCGAAAATTCCGTATCTGGAAGAGTTACACTTGGATGATAACTCAGTCTCGGCTGTTAGCATCGAAGAGGGAGCATTTCGAGACAGTAACTATCTGCGGCTGCTTTTTCTGTCCCGTAACCACCTTAGCACAATCCCGGGGGGCTTGCCCAGGACTATTGAGGAATTACGCCTGGATGACAATCGCATATCAACGATCTCTTCCCCATCACTTCATGGTCTCACAAGCCTGAAACGCCTGGTTTTAGATGGAAACTTGTTGAACAACCATGGTTTGGGTGACAAAGTTTTCTTCAACTTAGTAAACTTAACAGAGCTGTCCCT

form

lyophilized powder

form

lyophilized powder

form

lyophilized powder

form

lyophilized powder

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

10 - Combustible liquids

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Anna Skwarska et al.
Biochemical pharmacology, 95(4), 238-252 (2015-04-22)
Drugs targeting receptor tyrosine kinase FLT3 are of particular interest since activating FLT3-internal tandem duplication (ITD) mutations abundantly occur in fatal acute myeloid leukemias (AMLs). Imidazoacridinone C-1311, a DNA-reactive inhibitor of topoisomerase II, has been previously shown to be a

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