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Merck

M2069

D-(+)-Mannose

≥99% (GC), wood

Synonym(s):

D-Mannopyranose

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€64.80

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€677.00

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About This Item

Empirical Formula (Hill Notation):
C6H12O6
CAS Number:
3458-28-4
Molecular Weight:
180.16
UNSPSC Code:
12352201
NACRES:
NA.25
PubChem Substance ID:
24896601
EC Number:
222-392-4
Beilstein/REAXYS Number:
1564373
MDL number:
MFCD00064122

Key Documents

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Product Name

D-(+)-Mannose, ≥99% (GC), wood

SMILES string

OC[C@H]1OC(O)[C@@H](O)[C@@H](O)[C@@H]1O

InChI key

WQZGKKKJIJFFOK-QTVWNMPRSA-N

InChI

1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5+,6?/m1/s1

biological source

wood

assay

≥99% (GC)

form

powder

technique(s)

gas chromatography (GC): suitable

color

white to off-white

mp

133-140 °C (lit.)

solubility

water: 50 mg/mL, clear, colorless to faintly yellow

storage temp.

room temp

Quality Level

200

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This Item
M6020635794440-M
D-(+)-Mannose ≥99% (GC), wood

Sigma-Aldrich

M2069

D-(+)-Mannose

D-(+)-Mannose powder, BioReagent, suitable for cell culture

Sigma-Aldrich

M6020

D-(+)-Mannose

D-(+)-Mannose BioUltra, ≥99.5% (sum of enantiomers, HPLC)

Sigma-Aldrich

63579

D-(+)-Mannose

D-Mannose

Millipore

4440-M

D-Mannose

biological source

wood

biological source

plant (Spruce, Birch or Beech Wood, Glucose)

biological source

-

biological source

-

assay

≥99% (GC)

assay

≥99%

assay

≥99.5% (sum of enantiomers, HPLC)

assay

≥98% (GC, HPLC)

technique(s)

gas chromatography (GC): suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

-

technique(s)

-

solubility

water: 50 mg/mL, clear, colorless to faintly yellow

solubility

H2O: 50 mg/mL

solubility

H2O: 1 M, clear, colorless

solubility

water: 2.5 mg/mL

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

100

form

powder

form

powder

form

solid

form

solid

Analysis Note

Predominantly α-isomer

Application

D-(+)-Mannose, a C-2 epimer of D-glucose, is used in the formation of glycan structure and glycosylation.
D-Mannose has been used in a study to assess the synthesis of a family of amphiphilic glycopolymers. [1] It has also been used in a study to investigate the early detection of bronchiolitis obliterans after lung transplantation. [2]

Biochem/physiol Actions

Mannose, a six-carbon carbohydrate, is the C-2 epimer of glucose and a critical sugar for protein glycosylation. Mannose can also be utilized by the brain as an alternative energy source.

General description

Mannose is a monosaccharide.

Other Notes

From spruce, birch, or beech wood
To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
WXBF7856V
0000504663
0000504663
0000485513
0000485512

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Bithi Chatterjee et al.
Blood, 120(10), 2011-2020 (2012-07-14)
Dendritic cells (DCs) can capture extracellular antigens and load resultant peptides on to MHC class I molecules, a process termed cross presentation. The mechanisms of cross presentation remain incompletely understood, particularly in primary human DCs. One unknown is the extent
Fabian Suriano et al.
Biomaterials, 31(9), 2637-2645 (2010-01-16)
Polymers bearing pendant carbohydrates have a variety of biomedical applications especially in the area of targeted drug delivery. Here we report the synthesis of a family of amphiphilic block glycopolymers containing d glucose, d galactose and d mannose via metal-free
Steven J Budd et al.
Respiratory research, 13, 56-56 (2012-07-06)
Long-term lung allograft survival is limited by bronchiolitis obliterans syndrome (BOS). Mannose binding lectin (MBL) belongs to the innate immune system, participates in complement activation, and may predispose to graft rejection. We investigated mannose binding (MBL) during cold ischemia and
Troels R Kjaer et al.
Infection and immunity, 81(2), 452-459 (2012-11-28)
The three human ficolins (H-, L-, and M-ficolins) and mannan-binding lectin are pattern recognition molecules of the innate immune system mediating activation of the lectin pathway of the complement system. These four human proteins bind to some microorganisms and may
Conghui Liu et al.
Frontiers in immunology, 11, 1379-1379 (2020-08-15)
Cluster of differentiation 63 (CD63), a four-transmembrane glycoprotein in the subfamily of tetraspanin, has been widely recognized as a gateway from the infection of foreign invaders to the immune defense of hosts. Its role in Pacific oyster Crassostrea gigas is
View All Related Papers

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Questions

1–2 of 2 Questions  

  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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