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Merck

1044800

USP

Atracurium besylate

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

2,2′-[1,5-Pentanediylbis[oxy(3-oxo-3,1-propanediyl)]]bis[1-[3,4-dimethoxyphenyl)methyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methylisoquinolinium]dibenzenesulfonate, BW-33A, Tracrium

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100 MG

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€406.00

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About This Item

Empirical Formula (Hill Notation):
C65H82N2O18S2
CAS Number:
64228-81-5
Molecular Weight:
1243.48
NACRES:
NA.24
PubChem Substance ID:
329749081
UNSPSC Code:
41116107
MDL number:
MFCD00797403

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Product Name

Atracurium besylate, United States Pharmacopeia (USP) Reference Standard

InChI key

XXZSQOVSEBAPGS-UHFFFAOYSA-L

SMILES string

[O-]S(=O)(=O)c1ccccc1.[O-]S(=O)(=O)c2ccccc2.COc3ccc(CC4c5cc(OC)c(OC)cc5CC[N+]4(C)CCC(=O)OCCCCCOC(=O)CC[N+]6(C)CCc7cc(OC)c(OC)cc7C6Cc8ccc(OC)c(OC)c8)cc3OC

InChI

1S/C53H72N2O12.2C6H6O3S/c1-54(22-18-38-32-48(62-7)50(64-9)34-40(38)42(54)28-36-14-16-44(58-3)46(30-36)60-5)24-20-52(56)66-26-12-11-13-27-67-53(57)21-25-55(2)23-19-39-33-49(63-8)51(65-10)35-41(39)43(55)29-37-15-17-45(59-4)47(31-37)61-6;2*7-10(8,9)6-4-2-1-3-5-6/h14-17,30-35,42-43H,11-13,18-29H2,1-10H3;2*1-5H,(H,7,8,9)/q+2;;/p-2

grade

pharmaceutical primary standard

API family

atracurium

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

Gene Information

human ... CHRNA1(1134), CHRNB1(1140), CHRND(1144), CHRNE(1145), CHRNG(1146)

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1 of 4

This Item
Y0000424Y0000503Y0000504
Atracurium besylate United States Pharmacopeia (USP) Reference Standard

USP

1044800

Atracurium besylate

Atracurium besylate European Pharmacopoeia (EP) Reference Standard

Y0000424

Atracurium besylate

Atracurium for impurity F identification European Pharmacopoeia (EP) Reference Standard

Y0000503

Atracurium for impurity F identification

Atracurium for peak identification European Pharmacopoeia (EP) Reference Standard

Y0000504

Atracurium for peak identification

grade

pharmaceutical primary standard

grade

pharmaceutical primary standard

grade

pharmaceutical primary standard

grade

pharmaceutical primary standard

manufacturer/tradename

USP

manufacturer/tradename

EDQM

manufacturer/tradename

EDQM

manufacturer/tradename

EDQM

format

neat

format

neat

format

neat

format

neat

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

API family

atracurium

API family

atracurium

API family

atracurium

API family

atracurium

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Biochem/physiol Actions

Nicotinic acetylcholine receptor antagonist.

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Other Notes

Sales restrictions may apply.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Liivi Maddison et al.
Clinical hemorheology and microcirculation, 57(4), 367-374 (2013-10-02)
Microvascular alterations and intra-abdominal hypertension are both involved in development of organ failure. It is not known whether increased intra-abdominal pressure (IAP) is associated with microcirculatory perfusion derangements. Transient increase in IAP induced by pneumoperitoneum affects sublingual microcirculation. 16 laparoscopic
Morgan Le Guen et al.
Anesthesia and analgesia, 118(5), 946-955 (2014-04-12)
The α2-adrenergic agonist dexmedetomidine is a sedative and can be used as an adjunct to anesthetics. Our primary goal was thus to determine the extent to which dexmedetomidine reduces the requirement for propofol and remifentanil. This double-blinded, randomized study (NCT00921284)
P W M Janssen et al.
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society, 26(11), 1651-1662 (2014-09-25)
Spatiotemporal (ST) mapping has mainly been applied to ex vivo preparations of the gut. We report the results of ST mapping of the spontaneous and remifentanil-induced motility of circular and longitudinal muscles of the distal ileum in the postprandial anaesthetized
Ignacio Garutti et al.
Anesthesia and analgesia, 119(4), 815-828 (2014-07-19)
Lung resection surgery is associated with an inflammatory reaction. The use of 1-lung ventilation (OLV) seems to increase the likelihood of this reaction. Different prophylactic and therapeutic measures have been investigated to prevent lung injury secondary to OLV. Lidocaine, a
Mario Schietroma et al.
Journal of the American College of Surgeons, 220(5), 921-933 (2015-04-05)
This article has been retracted: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/about/our-business/policies/article-withdrawal). This article has been retracted at the request of the Editor-in-Chief. An independent statistical analysis based on the summary data tables and statistical results reported in the

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