Przejdź do zawartości
Merck

CHRNA1

cholinergic receptor, nicotinic, alpha 1 (muscle)

Synonimy:
ACHRA, ACHRD, CHRNA, CMS2A, FCCMS, SCCMS
Gatunek:
Human CHRNA1 (1134), Mouse Chrna1 (11435), Rat Chrna1 (79557), dog CHRNA1 (403757), domestic guinea pig Chrna1 (100729588), cow CHRNA1 (338070), chicken CHRNA1 (395608), sheep CHRNA1 (101110120), Zebrafish chrna1 (30725), naked mole-rat Chrna1 (101715747)
Identyfikator UniProtKB:
P02708, B4DRV6, D3DPE8
Identyfikator genu:
  • Human(1134) Summary: The muscle acetylcholine receptor consiststs of 5 subunits of 4 different types: 2 alpha subunits and 1 each of the beta, gamma, and delta subunits. This gene encodes an alpha subunit that plays a role in acetlycholine binding/channel gating. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Nov 2012]
  • Mouse(11435) cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle)
  • Rat(79557) cholinergic receptor, nicotinic, alpha 1 (muscle)
  • dog(403757) cholinergic receptor, nicotinic, alpha 1 (muscle)
  • domestic guinea pig(100729588) cholinergic receptor, nicotinic, alpha 1 (muscle)
  • cow(338070) cholinergic receptor, nicotinic, alpha 1 (muscle)
  • chicken(395608) cholinergic receptor, nicotinic, alpha 1 (muscle)
  • sheep(101110120) cholinergic receptor, nicotinic, alpha 1 (muscle)
  • Zebrafish(30725) cholinergic receptor, nicotinic, alpha polypeptide 1
  • naked mole-rat(101715747) cholinergic receptor, nicotinic, alpha 1 (muscle)

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Small Molecule - Agonist

Numer produktu
Opis
Gatunek
396966
Decamethonium bromide, Ion-Pair reagent, ≥99%,
Gatunek
human
N5511
(−)-Nicotine solution, 1.0 mg/mL, analytical standard, for drug analysis,
Gatunek
human, mouse, rat
N3876
(−)-Nicotine, ≥99% (GC), liquid,
Gatunek
human, mouse, rat
D1260
Decamethonium bromide, crystalline,
Gatunek
human
D5891
1,1-Dimethyl-4-phenylpiperazinium iodide, ≥98% (TLC or titration),
Gatunek
human, rat

Small Molecule - Antagonist

Numer produktu
Opis
Gatunek
112615
1-Octanol, ReagentPlus®, 99%,
Gatunek
mouse
293245
1-Octanol, suitable for HPLC, ≥99%,
Gatunek
mouse
297887
1-Octanol, anhydrous, ≥99%,
Gatunek
mouse
W280003
1-Octanol, ≥98%, FCC, FG,
Gatunek
mouse
W280011
1-Octanol, natural, ≥98%, FCC,
Gatunek
mouse

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
SAB1402724
Monoclonal Anti-CHRNA1 antibody produced in mouse, clone 2G5, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
MABN1618
Anti-Nicotinic Acetylchone Receptor alpha 1 Antibody, clone 7C8.2, clone 7C8.2, from mouse,
Reaktywność gatunkowa
human, rat
Zastosowanie
immunohistochemistry
western blot
AV34910
Anti-CHRNA1 (AB2) antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Zastosowanie
western blot
AV34909
Anti-CHRNA1 (AB1) antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human
Zastosowanie
western blot
ZRB2584
Anti-CHRNA1/ACHRA Antibody, clone 2G22 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
affinity binding assay
immunocytochemistry
immunofluorescence
immunohistochemistry
western blot

Small Molecule - Blocker

Numer produktu
Opis
Gatunek
H2138
Hexamethonium chloride, solid (hygroscopic),
Gatunek
human
H0879
Hexamethonium bromide, ,
Gatunek
human
T2265
Tetraethylammonium chloride, ≥98% (titration),
Gatunek
human
K3375
Kynurenic acid, ≥98%,
Gatunek
rat, human

Small Molecule - Mixed Agonist/Antagonist

Numer produktu
Opis
Gatunek
N5511
(−)-Nicotine solution, 1.0 mg/mL, analytical standard, for drug analysis,
Gatunek
human, mouse, rat
N3876
(−)-Nicotine, ≥99% (GC), liquid,
Gatunek
human, mouse, rat

esiRNA

Numer produktu
Opis
Gatunek
EHU061451
MISSION® esiRNA, targeting human CHRNA1,
Gatunek
human