This substance is synthetic organic. The product has been offered previously before 2023. See below for an example of the Certificate of Origin.
https://www.sigmaaldrich.com/coo/undefined/A5752/SHBL7005
A5752
Adrenochrome
>95% purity (HPLC), powder
Synonyme(s) :
3-Hydroxy-1-methyl-5,6-indolinedione
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25 MG
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730,00 €
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A propos de cet article
Formule empirique (notation de Hill) :
C9H9NO3
Numéro CAS:
Poids moléculaire :
179.17
Numéro CE :
Numéro MDL:
Code UNSPSC :
12171500
ID de substance PubChem :
Nomenclature NACRES :
NA.47
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Adrenochrome, ≥95% (HPLC)
Essai
≥95% (HPLC)
Forme
powder
Couleur
red to brown
εmax
3-4.5 at 485-490 nm in water
9.0-10.5 at 299-304 nm in water
Application(s)
diagnostic assay manufacturing
hematology
histology
Température de stockage
−20°C
Chaîne SMILES
CN1CC(O)C2=CC(=O)C(=O)C=C12
InChI
1S/C9H9NO3/c1-10-4-9(13)5-2-7(11)8(12)3-6(5)10/h2-3,9,13H,4H2,1H3
Clé InChI
RPHLQSHHTJORHI-UHFFFAOYSA-N
Catégories apparentées
1 of 4
Cet article | 214515 | D7008 | N5625 |
|---|---|---|---|
| color red to brown | color - | color pink to very dark red | color - |
| application(s) diagnostic assay manufacturing | application(s) diagnostic assay manufacturing | application(s) diagnostic assay manufacturing | application(s) diagnostic assay manufacturing |
| form powder | form powder | form powder | form powder |
| storage temp. −20°C | storage temp. room temp | storage temp. −20°C | storage temp. −20°C |
| assay ≥95% (HPLC) | assay - | assay ≥95% | assay >99% (TLC) |
| Quality Level 200 | Quality Level 200 | Quality Level 100 | Quality Level 200 |
Application
Adrenochrome has been used to study the effect of adrenochrome on coronary artery constriction in the rat heart.[1]
Actions biochimiques/physiologiques
Adrenochrome is an oxidation product of adrenaline.[2] It has been implicated in cardiotoxicity.[3][4] It is a short-lived cytotoxic molecule and is part of the leukocyte response used to kill bacteria.[5] Adrenochrome is also suggested to exhibit psychotomimetic effects.[6] It is used to determine superoxide dismutase activity.[7]
Produit(s) apparenté(s)
Réf. du produit
Description
Tarif
Code de la classe de stockage
11 - Combustible Solids
Classe de danger pour l'eau (WGK)
WGK 3
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
Équipement de protection individuelle
Eyeshields, Gloves, type N95 (US)
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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.
Janna Shainsky et al.
Applied and environmental microbiology, 75(14), 4711-4719 (2009-05-26)
Enantiopure sulfoxides are prevalent in drugs and are useful chiral auxiliaries in organic synthesis. The biocatalytic enantioselective oxidation of prochiral sulfides is a direct and economical approach for the synthesis of optically pure sulfoxides. The selection of suitable biocatalysts requires
The oxidative metabolism of catecholamines in the brain: a review.
Smythies J and Galzigna L
Biochimica et Biophysica Acta, 1380, 159-159 (1998)
The adrenochrome hypothesis of schizophrenia revisited.
Smythies J
Neurotoxicity Research, 4, 147-147 (2002)
Vera Marisa Costa et al.
Chemical research in toxicology, 20(8), 1183-1191 (2007-07-17)
High concentrations of circulating biogenic catecholamines often exist during the course of several cardiovascular disorders. Additionally, coronary dysfunctions are prominent and frequently related to the ischemic and reperfusion phenomenon (I/R) in the heart, which leads to the release of large
Viviana S Fluxá et al.
Nature protocols, 3(8), 1270-1277 (2008-08-21)
The adrenaline test for enzymes is a colorimetric enzyme assay based on the quantification of periodate-sensitive reaction products such as 1,2-diols and 1,2-aminoalcohols by back-titration of the oxidant with adrenaline to produce adrenochrome as an easily detectable red product. The
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Is this substance synthetic or naturally derived? Some download able Data on this product is dated 1/16/2023. Is this a relatively new substance?
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