B950-05
Bovine Renal Artery Smooth Muscle Cells: BRASMC (Cryovial)
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A propos de cet article
biological source
bovine renal artery (normal, tunica intima and media)
packaging
pkg of 500,000 cells
manufacturer/tradename
Cell Applications, Inc
growth mode
Adherent
karyotype
2n = 60
morphology
smooth muscle
technique(s)
cell culture | mammalian: suitable
relevant disease(s)
renal disease; cardiovascular diseases
shipped in
dry ice
storage temp.
−196°C
General description
Bovine Renal Artery Smooth Muscle Cells (BRASMC) are derived from tunica intima and tunica media of normal bovine renal arteries. They are cryopreserved at second passage and can be cultured and propagated at least 12 population doublings. Studies show cyclosporine-induced renal artery smooth muscle contraction is associated with increases in the phosphorylation of specific contractile regulatory proteins1. The renal artery smooth muscle is uniquely refractory to angiotensin stimulation and may be protective in the role of the kidney in regulating blood pressure through the renin-angiotensin system2.
Beall, A. et al, Biochem Biophys Acta., 1449(1):41-9 (1999)
Whitney, E.G. et al, J. Surg. Res. 61(2):307-10 (1996)
Products are for research use only. They are not intended for human, animal, or diagnostic application.
Animal tissues were USDA inspected.
Application
Biochem/physiol Actions
Preparation Note
- 2nd passage, >500,000 cells in Bovine Smooth Muscle Cell Basal Medium containing 10% FBS & 10% DMSO
- Can be cultured at least 12 doublings
Other Notes
1 of 1
Cet article | |||
|---|---|---|---|
| description - | description - | description - | description - |
| relevant disease(s) renal disease; cardiovascular diseases | relevant disease(s) cardiovascular diseases | relevant disease(s) diabetes; stroke; cardiovascular diseases | relevant disease(s) cardiovascular diseases |
| biological source bovine renal artery (normal, tunica intima and media) | biological source canine pulmonary artery (normal, tunica intima and media) | biological source bovine coronary artery (tunica intima and media) | biological source bovine pulmonary artery (tunica intima and media) |
| technique(s) cell culture | mammalian: suitable | technique(s) cell culture | mammalian: suitable | technique(s) cell culture | mammalian: suitable | technique(s) cell culture | mammalian: suitable |
| morphology smooth muscle | morphology smooth muscle | morphology smooth muscle | morphology smooth muscle |
| growth mode Adherent | growth mode Adherent | growth mode Adherent | growth mode Adherent |
| karyotype 2n = 60 | karyotype 2n = 78 | karyotype 2n = 60 | karyotype 2n = 60 |
Classe de stockage
11 - Combustible Solids
WGK
WGK 3
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
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