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Merck

1437450

USP

Methyl salicylate

United States Pharmacopeia (USP) Reference Standard

Synonyme(s) :

Essence de gaulthéria, Ester méthylique d’acide 2-hydroxybenzoïque

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A propos de cet article

Formule linéaire :
2-(HO)C6H4CO2CH3
Numéro CAS:
119-36-8
Poids moléculaire :
152.15
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329750276
MDL number:
MFCD00002214
Beilstein/REAXYS Number:
971516

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Nom du produit

Methyl salicylate, United States Pharmacopeia (USP) Reference Standard

InChI key

OSWPMRLSEDHDFF-UHFFFAOYSA-N

SMILES string

COC(=O)c1ccccc1O

InChI

1S/C8H8O3/c1-11-8(10)6-4-2-3-5-7(6)9/h2-5,9H,1H3

grade

pharmaceutical primary standard

vapor density

5.26 (vs air)

vapor pressure

1 mmHg ( 54 °C)

API family

methyl salicylate

autoignition temp.

847 °F

manufacturer/tradename

USP

refractive index

n20/D 1.536 (lit.)

bp

222 °C (lit.)

mp

−8-−7 °C (lit.)

density

1.174 g/mL at 25 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

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Cet article
PHR121476631PHL82239
Methyl salicylate United States Pharmacopeia (USP) Reference Standard

USP

1437450

Methyl salicylate

Methyl salicylate Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1214

Methyl salicylate

Methyl salicylate analytical standard

Supelco

76631

Methyl salicylate

Methyl salicylate phyproof® Reference Substance

PHL82239

Methyl salicylate

grade

pharmaceutical primary standard

grade

certified reference material, pharmaceutical secondary standard

grade

analytical standard

grade

primary reference standard

manufacturer/tradename

USP

manufacturer/tradename

-

manufacturer/tradename

-

manufacturer/tradename

PhytoLab

format

neat

format

neat

format

neat

format

-

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

application(s)

cleaning products
cosmetics
environmental
flavors and fragrances
food and beverages
personal care

application(s)

-

vapor density

5.26 (vs air)

vapor density

5.26 (vs air)

vapor density

5.26 (vs air)

vapor density

5.26 (vs air)

vapor pressure

1 mmHg ( 54 °C)

vapor pressure

1 mmHg ( 54 °C)

vapor pressure

1 mmHg ( 54 °C)

vapor pressure

1 mmHg ( 54 °C)

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Application

Methyl salicylate USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Other Notes

Sales restrictions may apply.

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Danger

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Repr. 2 - Skin Sens. 1B

Classe de stockage

10 - Combustible liquids

wgk

WGK 2

flash_point_f

204.8 °F - closed cup

flash_point_c

96 °C - closed cup

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Certificats d'analyse (COA)

Lot/Batch Number

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T Y Chan
Human & experimental toxicology, 15(9), 747-750 (1996-09-01)
Methyl salicylate (oil of wintergreen) is widely available in many over-the-counter liniments, ointments, lotions or medicated oils for the relief of musculoskeletal aches and pains. Ingestion of methyl salicylate poses the threat of severe, rapid-onset salicylate poisoning because of its
Jonathan E Davis
The Journal of emergency medicine, 32(1), 63-69 (2007-01-24)
Serious toxicity can result from exposure to small amounts of methyl salicylate. Methyl salicylate is widely available as a component in many over-the-counter brands of creams, ointments, lotions, liniments and medicated oils intended for topical application to relieve musculoskeletal aches
A Lapczynski et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 45 Suppl 1, S428-S452 (2007-11-23)
A toxicologic and dermatologic review of methyl salicylate when used as a fragrance ingredient is presented.
Taraka R Donti et al.
Disease models & mechanisms, 7(2), 271-280 (2013-11-26)
Mutations in subunits of succinyl-CoA synthetase/ligase (SCS), a component of the citric acid cycle, are associated with mitochondrial encephalomyopathy, elevation of methylmalonic acid (MMA), and mitochondrial DNA (mtDNA) depletion. A FACS-based retroviral-mediated gene trap mutagenesis screen in mouse embryonic stem
Wen-Po Chuang et al.
The New phytologist, 201(3), 928-939 (2013-12-07)
Some plant-derived anti-herbivore defensive proteins are induced by insect feeding, resist digestion in the caterpillar gut and are eliminated in the frass. We have identified several maize proteins in fall armyworm (Spodoptera frugiperda) frass that potentially play a role in
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