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Merck

1.02367

Magnesium chloride hexahydrate

cryst. EMPROVE® API Ph Eur,BP,JPC,USP

Synonym(s):

Magnesium dichloride

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About This Item

Linear Formula:
MgCl2 · 6H2O
CAS Number:
Molecular Weight:
203.30
MDL number:
UNSPSC Code:
12352302
EC Index Number:
232-094-6

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Agency

BP
JPC
Ph. Eur.
USP

Quality Level

product line

EMPROVE® API

form

solid

potency

8100 mg/kg LD50, oral (Rat)

pH

4.5-7.0 (20 °C, 50 g/L in H2O)

mp

117 °C (decomposition)

solubility

468.7 g/L

application(s)

liquid formulation
ophthalmics
parenterals
pharmaceutical
semi-solid formulation
solid formulation

storage temp.

2-25°C

SMILES string

O.O.O.O.O.O.Cl[Mg]Cl

InChI

1S/2ClH.Mg.6H2O/h2*1H;;6*1H2/q;;+2;;;;;;/p-2

InChI key

DHRRIBDTHFBPNG-UHFFFAOYSA-L

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1 of 4

This Item
1.018721.72571M7304
form

solid

form

crystalline, solid

form

solid

form

-

application(s)

liquid formulation
ophthalmics
parenterals
pharmaceutical
semi-solid formulation
solid formulation

application(s)

liquid formulation
pharmaceutical
solid formulation

application(s)

pharma/biopharma processes

application(s)

pharmaceutical (small molecule)

product line

EMPROVE® API

product line

-

product line

-

product line

-

agency

BP, Ph. Eur., JPC, USP

agency

JPC, Ph. Eur., USP

agency

-

agency

USP/NF, meets USP testing specifications

potency

8100 mg/kg LD50, oral (Rat)

potency

-

potency

-

potency

-

pH

4.5-7.0 (20 °C, 50 g/L in H2O)

pH

4.5-7.0 (20 °C, 50 g/L in H2O)

pH

4.5-7.0 (20 °C, 50 g/L in H2O)

pH

-

General description

We provide industry-leading production know-how and comprehensive regulatory support for high-quality APIs, backed by nearly 200 years of experience. From a complete portfolio of innovative folates to custom synthesis, our customized and scalable solutions meet your specific production needs. As part of our EMPROVE® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Magnesium chloride hexahydrate is used in clinical nutrition and in infusion. Magnesium Chloride hexahydrate cryst. Emprove® API is manufactured according to ICH Q7 guidelines. A CEP and an US-DMF are available.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Articles

Medicine for children poses unique formulation challenges compared to adults. Consider developmental physiology and age specifics when designing pharmaceuticals. Quality issues can severely impact patient safety. Therefore, excipient quality, supplier selection, and supply chain security are crucial, particularly for pediatric formulations.

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Developing formulations specifically for infants and children is increasingly important. To help you master these challenges effectively, we offer an extensive portfolio of well-established high-quality excipients and APIs for pediatric pharmaceutical formulations that are proven in practice.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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