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MAK108
PLTP Activity Assay Kit
Supplied by Roar Biomedical, Inc.
Synonym(s):
Phospholipid transfer protein activity assay kit
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usage
sufficient for 100 fluorometric tests
application(s)
pharmaceutical
detection method
fluorometric
relevant disease(s)
cardiovascular diseases
storage temp.
2-8°C
Gene Information
human ... PLTP(5360)
Related Categories
1 of 4
This Item | MAK109 | MAK110 | MAK106 |
|---|---|---|---|
| Gene Information human ... PLTP(5360) | Gene Information human ... LPL(4023) | Gene Information human ... MTTP(4547) | Gene Information human ... CETP(1071) |
| detection method fluorometric | detection method fluorometric | detection method fluorometric | detection method fluorometric |
| usage sufficient for 100 fluorometric tests | usage sufficient for 100 fluorometric tests | usage sufficient for 100 fluorometric tests | usage sufficient for 100 fluorometric tests |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C |
| application(s) pharmaceutical | application(s) pharmaceutical | application(s) pharmaceutical | application(s) pharmaceutical |
| relevant disease(s) cardiovascular diseases | relevant disease(s) gastrointestinal diseases; cardiovascular diseases | relevant disease(s) cardiovascular diseases | relevant disease(s) cardiovascular diseases |
General description
Phospholipid transfer protein (PLTP) is a protein present in normal human plasma. PLTP transfers phospholipids among lipoproteins in plasma.
Application
Suitable to determine Phospholipid transfer protein (PLTP) activity in plasma or serum (fresh or frozen) as well as other sources of PLTP.
Biochem/physiol Actions
The PLTP Activity Assay Kit includes proprietary substrates to detect PLTP mediated transfer of fluorescent substrate. Transfer activity results in increased fluorescent emission intensity (λEx = 465 nm/λEm = 535 nm) from the assay.
Storage Class Code
10 - Combustible liquids
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Ryan J Henderson et al.
Drug development and industrial pharmacy, 35(9), 1139-1146 (2009-04-22)
To investigate how different formulations of Amphotericin-B (Amp-B) affect the activity of phospholipid transfer protein (PLTP) when incubated with hyperlipidemic and normolipidemic plasma at physiological temperature (37 degrees C). Six hyperlipidemic and six normolipidemic plasma samples were collected and tested
Natacha Bellanger et al.
Arteriosclerosis, thrombosis, and vascular biology, 31(7), 1675-1681 (2011-04-30)
Low high-density lipoprotein (HDL) cholesterol levels are frequently observed in familial hypercholesterolemia (FH) and might be associated with functional alterations of HDL particles that may influence their efficaciousness in the reverse cholesterol transport pathway. We evaluated key steps of the
Alexina Orsoni et al.
Journal of lipid research, 53(4), 767-775 (2012-02-18)
In familial hypercholesterolemia (FH), low HDL cholesterol (HDL-C) levels are associated with functional alterations of HDL particles that reduce their capacity to mediate the reverse cholesterol transport (RCT) pathway. The objective of this study was to evaluate the consequences of
Axel Schlitt et al.
American journal of nephrology, 27(2), 138-143 (2007-02-20)
Phospholipid transfer protein (PLTP) is mainly involved in high-density lipoprotein (HDL) metabolism. The role of PLTP in atherogenesis is still controversial. We aimed to investigate PLTP activity in hemodialysis (HD) patients, a population which has an increased risk for the
Sander J Robins et al.
Atherosclerosis, 228(1), 230-236 (2013-03-13)
Cholesteryl ester transfer protein (CETP) and phospholipid transfer protein (PLTP) are two genetically-related plasma proteins involved in the exchange of cholesteryl esters and phospholipids between high-density lipoproteins (HDL) and other lipoproteins. Although low CETP and high PLTP activity both result
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Instructions
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Are products MAK107 and MAK108 compatible with mouse serum?
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Yes, but please be aware of possible sample hemolysis. Depending on the method of mouse sample collection, hemolysis may be common, which can interfere with fluorescence emission via color quenching.
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