Skip to Content
MilliporeSigma

1.03795

Cellvento® 4CHO COMP

chemically defined cell culture medium, ≤1.0 IU/mL endotoxin, pH 5.1-5.6(without supplement), pH 6.7-7.3(with supplement)

Sign In to View Organizational & Contract Pricing

Select a Size

Pricing and availability is not currently available.

About This Item

UNSPSC Code:
41106213

Skip To

Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Quality Level

description

shipped with cooling packs

product line

Cellvento®

form

dry powder

technique(s)

cell culture | mammalian: suitable (suspension)

storage temp.

2-8°C

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
14390C1.038401.25195
technique(s)

cell culture | mammalian: suitable (suspension)

technique(s)

cell culture | mammalian: suitable (suspension)

technique(s)

cell culture | mammalian: suitable (suspension)

technique(s)

cell culture | mammalian: suitable

form

dry powder

form

liquid

form

dry powder

form

dry powder

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

product line

Cellvento®

product line

Cellvento®

product line

Cellvento®

product line

Cellvento®

description

shipped with cooling packs

description

-

description

shipped with cooling packs

description

shipped with cooling pack

Quality Level

500

Quality Level

-

Quality Level

500

Quality Level

500

General description

Cellvento® 4CHO chemically defined cell culture medium has been specially developed for the growth of Chinese Hamster Ovary (CHO) cells and the expression of monoclonal antibodies and recombinant proteins in suspension culture. The formulation is of non-animal origin, chemically defined and contains no hydrolysates or components of unknown composition. Cellvento® 4CHO medium has been formulated without L-glutamine.

Application

Cellvento® 4CHO medium should be used as amplification medium and production medium in fed-batch applications. It is recommended to combine it with the companion feed supplement Cellvento® 4Feed in fed-batch manufacturing processes. The medium does not contain hypoxanthine and thymidine to allow a broad utilization, also in dhfr- transfected cells. The feed does not contain glucose to allow a fine tuning of the glucose concentration during fed-batch processes, thus allowing to minimize lactate production. The feed contains sources of both cysteine and tyrosine and should not be supplemented with any additional alkaline feed. This product is intended for research or further manufacturing but not for human or therapeutic use

Preparation Note

Formulated to contain 23.7 grams of powder per liter of medium.

Legal Information

CELLVENTO is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Sens. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 2


Stay compliant with GMP using the Emprove® Program

Accelerate qualification, maintain compliance, and save time with Emprove® Dossiers.

Download Dossiers

Note: you will be brought to EmproveSuite.com. Your username and password are separate from SigmaAldrich.com and may differ.

Register for free and access Emprove® Dossiers within minutes. Upgrade your subscription plan to unlock advanced and customized content in the Emprove® Suite

Not finding what you are looking for? Visit the Emprove® Program Help page.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Articles

Streamline upstream process monitoring with embedded Raman ready-to-use models for easy implementation and improved process understanding

Our step-by-step guide to optimizing media and feed combinations for upstream bioprocessing.

This case study walks through optimizing feed and media for upstream bioprocessing and how it translates to large-scale bioreactors.

Explore how low-impurity iron sources enhance consistency and control in recombinant protein production using Cellvento® 4CHO medium.

See All

Related Content

Enhance mAb and recombinant protein performance, efficacy, and stability with precise glycosylation modulation using the Cellvento® ModiFeed platform.

This page summarizes key considerations related to regulatory expectations for biomanufacturing including chemicals and polymeric materials. For chemicals, topics include nitrosamines and elemental impurities, and for polymeric materials such as filters and single-use assemblies, the focus is qualification and extractable and leachable testing.

Questions

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service