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MilliporeSigma

48-610MAG

MILLIPLEX® STAT Signaling Panel

Premixed STAT Phosphoprotein 5-Plex Cell Signaling Panel

Synonym(s):

Magnetic Bead STAT Kit, STAT Cell Signaling Kit, STAT activation detection, STAT pathway biomarker panel, STAT phosphorylation assay, STAT signaling panel, immune signaling phosphoprotein assay, rat STAT multiplex

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96 WELLS

$2,150.00

$2,150.00


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About This Item

UNSPSC Code:
12161503
NACRES:
NA.47
eCl@ss:
32161000

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Product Name

MILLIPLEX® STAT Signaling Panel,

Quality Level

description

Premixed STAT Phosphoprotein 5-Plex Cell Signaling Panel

species reactivity

human

technique(s)

multiplexing: suitable

input

cell lysate

packaging

pkg of 1 ea

manufacturer/tradename

Milliplex®

detection method

fluorometric (Luminex® xMAP® technology)

shipped in

wet ice

storage temp.

2-8°C

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This Item
48-623MAG48-621MAG48-690MAG
species reactivity

human

species reactivity

human, mouse

species reactivity

mouse, human, rat

species reactivity

human

manufacturer/tradename

Milliplex®

manufacturer/tradename

Milliplex®

manufacturer/tradename

Milliplex®

manufacturer/tradename

Milliplex®

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

technique(s)

multiplexing: suitable

technique(s)

multiplexing: suitable

technique(s)

multiplexing: suitable

technique(s)

multiplexing: suitable

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

detection method

fluorometric (Luminex xMAP)

detection method

fluorometric (Luminex® xMAP®)

detection method

fluorometric (Luminex® xMAP®)

detection method

fluorometric (Luminex xMAP)

General description

This panel targets phosphorylated STAT proteins, which are critical mediators of cytokine and growth factor signaling. STAT1 (pY701) and STAT3 (pY705, pS727) are involved in immune response, inflammation, and cell survival. STAT5A/B (pY694/699) plays a role in hematopoiesis and immune cell development. STAT6 (pY641) is primarily activated by IL-4 and IL-13, contributing to Th2 cell differentiation and allergic responses.

Application

MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze 5 analytes in cell lysate samples.

Analytes Included: STAT1 (pY701), STAT3 (pS727), STAT3 (pY705), STAT5A/B (pY694/699), STAT6 (pY641)

Assay Characteristics: Refer to the assay protocol for details on cross-reactivity, buffer compatibility, lysate control, and recommended loading control (MAPmate Control Assays).

Features and Benefits

  • Simultaneously detect 5 phosphorylated STAT proteins involved in cytokine and growth factor signaling
  • Includes STAT1, STAT3, STAT5A/B, and STAT6 for focused pathway analysis
  • Magnetic bead-based format ensures reproducibility and efficient processing
  • Compatible with cell lysates from immune and cancer-related studies
  • Ideal for inflammation, immune regulation, and oncology research
  • Fast, convenient alternative to Western Blotting and immunoprecipitation procedures

Legal Information

Luminex is a registered trademark of Luminex Corp
MAPMATE is a trademark of Merck KGaA, Darmstadt, Germany
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

Disclaimer

For research use only. Not for use in diagnostic procedures.

Label License/Sticker for Assay Product:

By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.

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Danger

Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

wgk

WGK 3

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 2 - ED ENV 1 - Eye Dam. 1 - Skin Irrit. 2


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Related Content

See how multiplexing the inflammation signaling pathway with MILLIPLEX® inflammation assays or cell signaling assays can help researchers bridge the gap between immunology and cell signaling, including investigating T cell signaling, Th Cell differentiation, inflammatory response signaling, and sepsis signaling.

Uncover how cells communicate with MILLIPLEX® cell signaling multiplex assays. Multiplexing with cell signaling phosphoprotein assays based on Luminex® xMAP® technology helps researchers measure phosphoproteins and total proteins within the same or different pathways from a single sample.

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Questions

  1. Is there a mouse kit similar to 48-610MAG, which can detect mouse phospho-STAT 1, 3, and 5 proteins?

    1 answer
    1. The kit is compatible with mouse samples for STAT1, 3, and 5 only. However, it is a nonconfigurable kit, so the full panel would need to be purchased.

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