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A7631

(+)-Sodium L-ascorbate

crystalline, ≥98%

(+)-Sodium L-ascorbate

Synonym(s):

L(+)-Ascorbic acid sodium salt, Vitamin C sodium salt

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About This Item

Empirical Formula (Hill Notation):
C6H7NaO6
CAS Number:
134-03-2
Molecular Weight:
198.11
NACRES:
NA.79
PubChem Substance ID:
24891261
eCl@ss:
34058010
UNSPSC Code:
12352205
EC Number:
205-126-1
MDL number:
MFCD00082340
Beilstein/REAXYS Number:
3767246

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Product Name

(+)-Sodium L-ascorbate, crystalline, ≥98%

InChI key

PPASLZSBLFJQEF-RXSVEWSESA-M

InChI

1S/C6H8O6.Na/c7-1-2(8)5-3(9)4(10)6(11)12-5;/h2,5,7-10H,1H2;/q;+1/p-1/t2-,5+;/m0./s1

SMILES string

[Na+].OC[C@H](O)[C@H]1OC(=O)C(O)=C1[O-]

biological source

synthetic

assay

≥98%

form

crystalline

technique(s)

HPLC: suitable

color

white to off-white

mp

220 °C (dec.) (lit.)

Quality Level

300

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Show Differences

1 of 4

This Item
11140A4034PHR1279
(+)-Sodium L-ascorbate crystalline, ≥98%

Sigma-Aldrich

A7631

(+)-Sodium L-ascorbate

(+)-Sodium L-ascorbate BioXtra, ≥99.0% (NT)

Sigma-Aldrich

11140

(+)-Sodium L-ascorbate

(+)-Sodium L-ascorbate powder, BioReagent, suitable for cell culture

Sigma-Aldrich

A4034

(+)-Sodium L-ascorbate

Sodium ascorbate Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1279

Sodium ascorbate

technique(s)

HPLC: suitable

technique(s)

-

technique(s)

cell culture | mammalian: suitable, cell culture | plant: suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

assay

≥98%

assay

≥99.0% (NT)

assay

≥98%

assay

-

biological source

synthetic

biological source

-

biological source

synthetic (organic)

biological source

-

form

crystalline

form

powder or crystals

form

powder

form

-

color

white to off-white

color

white

color

white to off-white

color

-

mp

220 °C (dec.) (lit.)

mp

220 °C (dec.) (lit.)

mp

220 °C (dec.) (lit.)

mp

220 °C (dec.) (lit.)

Application

(+)-Sodium L-ascorbate has been used:
  • as a component of cutting solution for storing brain slices of rats[1]
  • as a component of patch pipette internal solution for imaging Ca2+ transients evoked by action potential in rat brain slices[1]
  • as a supplement for arterial smooth muscle cell (SMC) cultures to encourage collagen production[2]

Biochem/physiol Actions

Ascorbic acid exhibits anti-oxidant properties. It is a primary substrate for detoxifying hydrogen peroxide.[3] Ascorbic acid is a co-factor for the synthesis of adrenal steroids and catecholamines.[4] L-Ascorbic acid (Vitamin C) is a water soluble molecule used in a wide variety of applications, including cell culture, as a reducing agent that helps reduce oxidative stress. L-Ascorbate can be regenerated by biological systems.

Disclaimer

May darken in storage.

General description

Ascorbic acid, also known as vitamin C, is a water-soluble vitamin.[3] L-Ascorbic acid is a reducing agent.[5]

Storage Class

11 - Combustible Solids

wgk

WGK 1

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
0000512552
0000512552
0000511924
0000511924
0000484561

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Exogenous ascorbic acid (vitamin C) increases resistance to salt stress and reduces lipid peroxidation
Shalata A and Neumann P M
Journal of Experimental Botany, 52(364), 2207-2211 (2001)
Imaging calcium concentration dynamics in small neuronal compartments
Yasuda R, et al.
Science's STKE : Signal Transduction Knowledge Environment, 219, pl5-pl5 (2004)
Differential roles of endothelin-1 in angiotensin II-induced atherosclerosis and aortic aneurysms in apolipoprotein E-null mice
Suen RS, et al.
The American Journal of Pathology, 179(3), 1549-1559 (2011)
Vitamin C is an important cofactor for both adrenal cortex and adrenal medulla
Patak P, et al.
Endocrine Research, 30(4), 871-875 (2004)
Marc Gentzel et al.
Methods (San Diego, Calif.), 164-165, 67-72 (2019-04-07)
The identification of bona fide protein-protein interactions and the mapping of proteomes was greatly enhanced by protein tagging for generic affinity purification methods and analysis by mass spectrometry (AP-MS). The high quality of AP-MS data permitted the development of proteomic
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Articles

Dietary Antioxidants

Antioxidants protect biological systems from oxidative damage produced by oxygen-containing free radicals and from redoxactive transition metal ions such as iron, copper, and cadmium.

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Questions

1–3 of 3 Questions  

  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. The storage temperature of L-Ascorbic acid(Cat# A4544) and Ascorbate(Cat# A7631) ?

    1 answer

    1. Both products may be stored at room temperature.

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  3. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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