CASP9
caspase 9, apoptosis-related cysteine peptidase
Synonymes:
APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56
Espèce(s):
Human CASP9 (842), Mouse Casp9 (12371), Rat Casp9 (58918), domestic cat CASP9 (768260), naked mole-rat Casp9 (101702898), cow CASP9 (100140945), Horse CASP9 (100054331), dog CASP9 (487432), chicken CASP9 (426970), sheep CASP9 (101110953) ...Plus
ID UniProtKB:
ID du gène:
- Human(842) Summary: This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein can undergo autoproteolytic processing and activation by the apoptosome, a protein complex of cytochrome c and the apoptotic peptidase activating factor 1; this step is thought to be one of the earliest in the caspase activation cascade. This protein is thought to play a central role in apoptosis and to be a tumor suppressor. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]
- Mouse(12371) caspase 9
- Rat(58918) caspase 9, apoptosis-related cysteine peptidase
- domestic cat(768260) caspase 9, apoptosis-related cysteine peptidase
- naked mole-rat(101702898) caspase 9, apoptosis-related cysteine peptidase
- cow(100140945) caspase 9, apoptosis-related cysteine peptidase
- Horse(100054331) caspase 9, apoptosis-related cysteine peptidase
- dog(487432) caspase 9, apoptosis-related cysteine peptidase
- chicken(426970) caspase 9, apoptosis-related cysteine peptidase
- sheep(101110953) caspase 9, apoptosis-related cysteine peptidase
- domestic guinea pig(100714954) caspase 9, apoptosis-related cysteine peptidase
- Zebrafish(492763) caspase 9, apoptosis-related cysteine protease
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Antibodies
Numéro du produit
Description
Espèces réactives
Application
Anti-Caspase 9 antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human
Application
western blot
Anti-Caspase-9 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Espèces réactives
human, mouse, rat
Application
ELISA
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-Caspase 9 antibody produced in rabbit, ,
Espèces réactives
human, mouse, rat
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-Caspase 9 Antibody, clone 2-23, clone 2-23, Chemicon®, from mouse,
Espèces réactives
human, mouse
Application
immunohistochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-Caspase-9 Antibody, clone 1G22 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Espèces réactives
human
Application
affinity binding assay
immunohistochemistry
western blot
immunohistochemistry
western blot
Small Molecule - Inhibitor
Kits
Numéro du produit
Description
Espèce(s)
Caspase 9 Colorimetric Activity Assay Kit, LEHD, Caspase-9 Colorimetric Activity Assay Kits provide a simple & convenient means for assaying the activity of caspases that recognize the LEHD.,
Espèce(s)
human
Caspase 9 Colorimetric Activity Assay Kit, LEHD, Caspase-9 Colorimetric Activity Assay Kits provide a simple & convenient means for assaying the activity of caspases that recognize the LEHD.,
Espèce(s)
human
esiRNA
Small Molecule - Substrate
Numéro du produit
Description
Espèce(s)
N-Acetyl-Leu-Glu-His-Asp-7-amido-4-trifluoromethylcoumarin, ≥95% (HPLC), powder,
Espèce(s)
mouse, rat, human