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Merck

75746

Dodécylsulfate de sodium

greener alternative

≥99.0% (GC), dust-free pellets

Synonyme(s) :

Dodécyl sulfate sodium salt, Dodécylsulfate de sodium, Lauryl sulfate sodium salt, SDS, Sodium lauryl sulfate

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250 G

74.40 CHF

1 KG

285.00 CHF

74.40 CHF


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A propos de cet article

Formule linéaire :
CH3(CH2)11OSO3Na
Numéro CAS:
Poids moléculaire :
288.38
NACRES:
NA.25
PubChem Substance ID:
eCl@ss:
39093306
UNSPSC Code:
12161900
EC Number:
205-788-1
MDL number:
Beilstein/REAXYS Number:
3599286

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Nom du produit

Dodécylsulfate de sodium, ≥99.0% (GC), dust-free pellets

InChI

1S/C12H26O4S.Na/c1-2-3-4-5-6-7-8-9-10-11-12-16-17(13,14)15;/h2-12H2,1H3,(H,13,14,15);/q;+1/p-1

InChI key

DBMJMQXJHONAFJ-UHFFFAOYSA-M

SMILES string

[Na+].CCCCCCCCCCCCOS([O-])(=O)=O

description

anionic

assay

≥99.0% (GC)

form

rod

mol wt

average mol wt 18,000

Quality Level

greener alternative product characteristics

Catalysis
Learn more about the Principles of Green Chemistry.

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aggregation number

62

loss

≤5% loss on drying

CMC

7-10 (lit.)

mp

204 - 207  °C (399 - 405 °F)
204-207 °C (lit.)

transition temp

cloud point >100 °C(lit.)

solubility

H2O: soluble 0.29 gm in 10ml, clear, colorless
H2O: 0.1 M at 20 °C, clear, colorless
130 g/L at 20 °C (68 °F)

density

1 g/cm3

anion traces

chloride (Cl-): ≤200 mg/kg

cation traces

Ca: ≤25 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤10 mg/kg
K: ≤200 mg/kg
Mg: ≤20 mg/kg
Mn: ≤5 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Zn: ≤5 mg/kg

HLB

40(lit.)

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Cet article
L6026436143L4509
form

rod

form

powder

form

solid

form

powder

assay

≥99.0% (GC)

assay

≥99.0% (GC)

assay

≥99.0%

assay

≥98.5% (GC)

aggregation number

62

aggregation number

62

aggregation number

-

aggregation number

62

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

description

anionic

description

anionic

description

anionic, 62

description

anionic

mol wt

average mol wt 18,000

mol wt

micellar avg mol wt 18,000

mol wt

288.38 g/mol

mol wt

micellar avg mol wt 18,000

Application

Détergent anionique
Sodium dodecyl sulfate (SDS) has been used:
  • as a negatively charged surfactant to study its effects on filtration flux and membrane fouling during the microfiltration of the surfactant-stabilized oil emulsion
  • as a component of plant extraction buffer, and transferring buffer for western blot
  • as a component of 5× Laemmli sample buffer (5× LB) and 10× SDS running buffer for sodium dodecyl-sulfate polyacrylamide gel electrophoresis (SDS-PAGE) and immunoblot

Biochem/physiol Actions

Sodium dodecyl sulfate (SDS) effectively binds to the positively charged and the hydrophobic residues of proteins via sulfate groups and alkyl chains. It functions as a vital detergent in the domain of structural biology and protein folding/unfolding studies. SDS can stimulate the creation of α-helices in a protein structure. It has the ability to promote cooperative unfolding in several proteins including bovine serum albumin (BSA), β-lactoglobulin, α-lactalbumin, and hen egg-white lysozyme structures at elevated concentrations. 

Features and Benefits

  • Tested to confirm low levels of heavy metal contamination, ensuring suitability for various applications
  • Tested for trace levels of Anions and Cations
  • High-purity product ideal for biochemical research purposes

General description

Sodium dodecyl sulfate (SDS) is an organic sodium salt used as both a detergent and a protein denaturant in biochemical research. Its unique structure includes a long-chain aliphatic group with a negatively charged sulfate, making it an effective agent for denaturing proteins. This property is especially valuable in electrophoresis, a technique used to separate and analyze macromolecules like proteins. SDS, with its negative charge, interacts with proteins and lipids to create micellar structures, aiding in solubilizing and stabilizing these biomolecules.
We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. This product is used as a surfactant to enhance catalysis.  Click here for more information.

Other Notes

For additional information on our range of Biochemicals, please complete this form.

pictograms

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Danger

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Skin Irrit. 2

Classe de stockage

11 - Combustible Solids

wgk

WGK 2

flash_point_f

338.0 °F

flash_point_c

170 °C

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

D Wessel et al.
Analytical biochemistry, 138(1), 141-143 (1984-04-01)
A rapid method based on a defined methanol-chloroform-water mixture for the quantitative precipitation of soluble as well as hydrophobic proteins from dilute solutions (e.g., column chromatography effluents) has been developed. The effectiveness of this method is not affected by the
J Kamerbeek et al.
Journal of clinical microbiology, 35(4), 907-914 (1997-04-01)
Widespread use of DNA restriction fragment length polymorphism (RFLP) to differentiate strains of Mycobacterium tuberculosis to monitor the transmission of tuberculosis has been hampered by the need to culture this slow-growing organism and by the level of technical sophistication needed
K Fujimoto
Journal of cell science, 108 ( Pt 11), 3443-3449 (1995-11-01)
We propose a new electron microscopic method, the sodium dodecylsulphate (SDS)-digested freeze-fracture replica labeling technique, to study the two-dimensional distribution of integral membrane proteins in cellular membranes. Unfixed tissue slices were frozen with liquid helium, freeze-fractured, and replicated in a
The gross conformation of protein-sodium dodecyl sulfate complexes.
J A Reynolds et al.
The Journal of biological chemistry, 245(19), 5161-5165 (1970-10-10)
Kazuya Ishikawa et al.
Nature communications, 5, 5430-5430 (2014-11-13)
Pathogen effector proteins are delivered to host cells to suppress plant immunity. However, the mechanisms by which effector proteins function are largely unknown. Here we show that expression of XopP(Xoo), an effector of rice pathogen Xanthomonas oryzae pv. oryzae, in

Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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