Adenosine 5′-diphosphate sodium salt is soluble at up to 50mg/mL in H2O. Sodium salts frequently increase the solubility of poorly soluble molecules and compounds.
A2754
Adénosine 5′-diphosphate sodium salt
≥95% (HPLC), bacterial, powder
Synonyme(s) :
Sel sodique de l’ADP, ADP
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100 MG
35.90 CHF
500 MG
110.00 CHF
1 G
195.00 CHF
5 X 1 G
834.00 CHF
35.90 CHF
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A propos de cet article
Formule empirique (notation de Hill) :
C10H15N5O10P2
Numéro CAS:
Poids moléculaire :
427.20
UNSPSC Code:
41106305
eCl@ss:
32160414
PubChem Substance ID:
NACRES:
NA.51
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Adénosine 5′-diphosphate sodium salt, bacterial, ≥95% (HPLC)
SMILES string
[Na].Nc1ncnc2n(cnc12)C3OC(COP(O)(=O)OP(O)(O)=O)C(O)C3O
InChI
1S/C10H15N5O10P2/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(24-10)1-23-27(21,22)25-26(18,19)20/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H2,11,12,13)(H2,18,19,20)/t4-,6-,7-,10-/m1/s1
InChI key
XTWYTFMLZFPYCI-KQYNXXCUSA-N
biological source
bacterial
assay
≥95% (HPLC)
form
powder
solubility
water: 50 mg/mL, clear to hazy, colorless
storage temp.
−20°C
Quality Level
Gene Information
human ... HSP90AA1(3320), P2RY1(5028)
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Catégories apparentées
1 of 4
Cet article | A5763 | A5638 | A4386 |
|---|---|---|---|
| biological source bacterial | biological source synthetic (inorganic) | biological source - | biological source bacterial |
| Quality Level 300 | Quality Level 200 | Quality Level 200 | Quality Level 200 |
| form powder | form powder | form powder | form crystalline |
| assay ≥95% (HPLC) | assay ≥96% | assay ≥95% | assay ≥95% (HPLC) |
| storage temp. −20°C | storage temp. −20°C | storage temp. −20°C | storage temp. −20°C |
| Gene Information human ... HSP90AA1(3320), P2RY1(5028) | Gene Information - | Gene Information - | Gene Information - |
Application
Le sel de sodium de l'adénosine 5′-diphosphate a été utilisé :
- comme témoin positif de l'agrégation plaquettaire pour analyser l'activité anti-plaquettes de la désintégrine par agrégométrie.
- dans la préparation d'une solution-mère pour un test de stress mitochondrial.
- comme témoin positif dans une analyse de cytométrie en flux pour étudier l'effet de la protéine C réactive pentamère (pCRP) et de la CRP monomère (mCRP) sur l'expression de CD62p (sélectine P) par les plaquettes.
- comme agoniste des plaquettes pour stimuler l'agrégation plaquettaire.[1]
General description
L'adénosine 5′-diphosphate (ADP) est un nucléotide de l'adénosine impliqué dans le stockage de l'énergie et le métabolisme des acides nucléiques via sa conversion en ATP par les FOF1-ATP synthases. L'ADP peut aussi être obtenu par une réaction avec l'adénylate monophosphate (AMP) catalysée par l'adénylate kinase. L'ADP est un agoniste des plaquettes sécrété par les granules denses plaquettaires. Il promeut l'activation plaquettaire en interagissant avec les récepteurs de l'ADP P2Y1 et P2Y12. Lors de la conversion de l'ADP en adénosine par les ecto-ADPases, l'activation plaquettaire est inhibée via les récepteurs de l'adénosine.
Classe de stockage
11 - Combustible Solids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
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ADP is considered a weak platelet agonist due to the limited aggregation responses it induces in vitro at physiological concentrations of extracellular Ca(2+) [(Ca(2+) )(o) ]. Lowering [Ca(2+) ](o) paradoxically enhances ADP-evoked aggregation, an effect that has been attributed to
Protocoles
HILIC separation is an alternative that permits sensitive MS detection and without the use of ion-pair reagents.
ZIC®-cHILIC is a densely bonded zwitterionic stationary phase with phosphorylcholine functional groups covalently attached to silica.
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which ADP is readily soluble in water, the sodium salt or the product with out sodium salt
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Is product A2754 FDA approved for use in testing patient samples (Platelet aggregation/function testing) at this time?
1 answer-
No, the product A2754 is not FDA approved for testing patient samples for platelet aggregation/function testing at this time.
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What is the solution stability of Adenosine 5'-diphosphate (ADP) sodium salt, Product A2754?
1 answer-
ADP sodium salt is stable in solution for several months when stored at pH 7 and at -20 °C. When a solution is stored at pH 7 and 4 °C, the solution is stable for several days. It is unstable in acid.
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What are the spectral properties of Adenosine 5'-diphosphate (ADP) sodium salt, Product A2754?
1 answer-
The millimolar extinction coefficient of a pH 7 solution of ADP sodium salt is 15.4 at the absorbance maximum wavelength of 259 nm.
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What is the solubility of Adenosine 5'-diphosphate (ADP) sodium salt, Product A2754?
1 answer-
ADP sodium salt is soluble in water at a concentration of 50 mg/mL.
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I see that the molecular weight for Adenosine 5'-diphosphate (ADP) sodium salt, Product A2754, on the website does not include sodium, water and solvent content. Why is that?
1 answer-
The amount of sodium, water and solvent for ADP sodium salt will vary from lot to lot. The specific lot information can be found on the certificate of analysis located at our website. To obtain the "true" molecular weight (so that one can calculate the molarity of a solution), the sodium, water and solvent amount must be added to the molecular weight listed on the website.
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What is the Department of Transportation shipping information for this product?
1 answer-
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
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