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700147P

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PhotoClick Cholesterol

Avanti Research™ - A Croda Brand

Sinonimo/i:

hex-5-yn-1-yl 4-((3S,5S)-3-hydroxy-10, 13-dimethyl-1,2,3,4,5,7,8,9,10,11,12,13,14,15,16,17-hexadecahydrospiro[cyclopenta[a]phenanthrene-6,3′-diazirin]-17-yl)pentanoate

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Voi/SKUDisponibilitàPrezzo
100 μg
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CHF 279.00
250 μg
Per conoscere la disponibilità, visualizza il carrello
CHF 526.00

Informazioni su questo articolo

Formula empirica (notazione di Hill):
C30H46N2O3
Numero CAS:
1485490-47-8
Peso molecolare:
482.70
MDL number:
MFCD00870345
NACRES:
NA.25
UNSPSC Code:
12352211

CHF 279.00

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Nome del prodotto

PhotoClick Cholesterol, Hex-5′-ynyl 3β-hydroxy-6-diazirinyl-5α-cholan-24-oate, powder

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 100 μg (with stopper and crimp cap (700147P-100ug)), pkg of 1 × 250 μg (with stopper and crimp cap (700147P-250ug))

manufacturer/tradename

Avanti Research™ - A Croda Brand 700147P

lipid type

click reagents

shipped in

dry ice

storage temp.

−20°C

General description

PhotoClick Cholesterol is a synthetic analog of cholesterol and is photoreactive. It comprises the alkyne group.
PhotoClick Cholesterol is a clickable, photoreactive sterol probe for use in combination with quantitative mass spectrometry to globally map cholesterol-protein interactions directly in living cells. In addition to the UV-activatable cross-linking diazirine group that reacts with proteins, the sterol contains an alkyne group for incorporation of reporter and affinity tags through click-chemistry.

Application

PhotoClick Cholesterol has been used:
  • in lysosome-associated membrane protein 1 (LAMP1) crosslinking studies
  • as an analog of cholesterol in binding and competition assay of sterol binding proteins from yeast
  • as a conjugate with the ectodomain of lysosomal integral membrane protein-2 (LIMP-2)

Biochem/physiol Actions

PhotoClick Cholesterol serves as a probe for tracking cholesterol-binding proteins. The copper-catalyzed azide-alkyne cycloaddition is the basis for its probe functionality. The alkyne group is essential for the click chemistry property. Its binding to partners is mediated by photocrosslinking.

Packaging

2 mL Amber Serum Vial with Stopper and Crimp Cap (700147P-100ug)
2 mL Amber Serum Vial with Stopper and Crimp Cap (700147P-250ug)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

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900602P810250C810253P
PhotoClick Cholesterol Hex-5′-ynyl 3β-hydroxy-6-diazirinyl-5α-cholan-24-oate, powder

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700147P

PhotoClick Cholesterol

Photoclick C6 Ceramide Avanti Research™ - A Croda Brand

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900602P

Photoclick C6 Ceramide

25-NBD Cholesterol Avanti Research™ - A Croda Brand 810250C

Avanti

810250C

25-NBD Cholesterol

dehydroergosterol (DHE) ergosta-5,7,9(11),22-tetraen-3β-ol, powder

Avanti

810253P

dehydroergosterol (DHE)

description

Hex-5′-ynyl 3β-hydroxy-6-diazirinyl-5α-cholan-24-oate, powder

description

Avanti Research™ - A Croda Brand

description

Avanti Research™ - A Croda Brand 810250C

description

ergosta-5,7,9(11),22-tetraen-3β-ol, powder

assay

>99% (TLC)

assay

>99% (TLC)

assay

>99% (TLC)

assay

>99% (TLC)

manufacturer/tradename

Avanti Research™ - A Croda Brand 700147P

manufacturer/tradename

Avanti Research™ - A Croda Brand

manufacturer/tradename

Avanti Research™ - A Croda Brand 810250C

manufacturer/tradename

Avanti Research™ - A Croda Brand 810253P

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−70°C

form

powder

form

powder

form

liquid

form

powder

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

packaging

pkg of 1 × 250 μg (with stopper and crimp cap (700147P-250ug)), pkg of 1 × 100 μg (with stopper and crimp cap (700147P-100ug))

packaging

package of 1 × 250 μg

packaging

pkg of 1 × 1 mL (810250C-1mg), pkg of 1 × 1 mL (810250C-10mg), pkg of 1 × 1 mL (810250C-5mg)

packaging

pkg of 1 × 1 mg (with stopper and crimp cap (810253P-1mg))

Classe di stoccaggio

11 - Combustible Solids

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