50847

Gramicidin C from Bacillus brevis

~90% (HPLC)

• Numero CAS: 9062-61-7
• MDL number: MFCD00466945
• UNSPSC Code: 51283112
• NACRES: NA.85
• eCl@ss: 32035490

Proprietà

• biological source: Bacillus brevis
• assay: ~90% (HPLC)
• form: powder
• impurities: ≤5% water
• color: white to off-white
• antibiotic activity spectrum: Gram-negative bacteria, Gram-positive bacteria
• mode of action: cell membrane | interferes, enzyme | inhibits
• storage temp.: 2-8°C
• SMILES string: CC(C)C[C@@H]1NC(=O)[C@H](CCCN)NC(=O)[C@@H](NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCN)NC(=O)[C@@H](NC(=O)[C@@H]4CCCN4C(=O)[C@@H](Cc5ccccc5)NC1=O)C(C)C)C(C)C
• InChI key: IUAYMJGZBVDSGL-JYFSIOBESA-N

Descrizione

General description

Chemical structure: peptide

Application

Gramicidin is a naturally occuring polypeptide antibiotic. It functions as a transmembrane ion channel and is used for studies on phospholipid bilayer membrane fluidity measured by lateral diffusion.

Biochem/physiol Actions

Naturally occuring polypeptide antibiotic with Tyr at position 11; functions as a transmembrane ion channel.

Gramicidin′s bactericidal activity is a result of increasing the permeability of the bacterial cell membrane. This allows inorganic monovalent cations to travel through unrestricted which thereby destroys the ion gradient between the cytoplasm and the extracellular environment .

Packaging

10mg

Other Notes

Keep container tightly closed in a dry and well-ventilated place.Keep in a dry place. Keep in a dry place.

Informazioni sulla sicurezza

• Classe di stoccaggio: 11 - Combustible Solids
• WGK: WGK 3
• Punto di infiammabilità (°F): Not applicable
• Punto di infiammabilità (°C): Not applicable
• DPI (dispositivi di protezione individuale): Eyeshields, Gloves, type N95 (US)