This product is soluble in water (0.25mg/ml), yielding a clear colorless solution.
B150
BQ-123
≥99%, sodium salt, lyophilized powder
Sinonimo/i:
BQ123, Cyclo(D-Trp-D-Asp-Pro-D-Val-Leu)
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Informazioni su questo articolo
Formula empirica (notazione di Hill):
C31H41N6O7 Na
Numero CAS:
Peso molecolare:
632.68
NACRES:
NA.32
PubChem Substance ID:
UNSPSC Code:
12352204
MDL number:
Assay:
≥99%
Form:
lyophilized powder
Prezzi e disponibilità al momento non sono disponibili
Servizio Tecnico
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Permettici di aiutartiQuality Segment
assay
≥99%
form
lyophilized powder
storage temp.
−20°C
SMILES string
[H][C@@]12CCCN1C(=O)[C@@H](CC(O)=O)NC(=O)[C@@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](NC2=O)C(C)C
InChI
1S/C31H42N6O7/c1-16(2)12-21-27(40)33-22(13-18-15-32-20-9-6-5-8-19(18)20)28(41)35-23(14-25(38)39)31(44)37-11-7-10-24(37)29(42)36-26(17(3)4)30(43)34-21/h5-6,8-9,15-17,21-24,26,32H,7,10-14H2,1-4H3,(H,33,40)(H,34,43)(H,35,41)(H,36,42)(H,38,39)/t21-,22+,23+,24-,26+/m0/s1
InChI key
VYCMAAOURFJIHD-PJNXIOHISA-N
Gene Information
human ... EDNRA(1909), EDNRB(1910)
rat ... Ednra(24326), Ednrb(50672)
Application
BQ-123 has been used as a selective endothelin-A receptor antagonist to study its effects on tumor necrosis factor α (TNFα)-induced human airway smooth muscle cells (HASMCs) proliferation. It is also used as endothelin-A receptor antagonist to study its effects on TNFα-induced granulocyte–macrophage colony-stimulating factor (GM-CSF) expression.
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Questo articolo | |||
|---|---|---|---|
| description ≥99%, sodium salt, lyophilized powder | description ≥95%, solid | description affinity isolated antibody, lyophilized powder | description affinity isolated antibody, buffered aqueous solution |
| assay ≥99% | assay ≥95% | assay - | assay - |
| form lyophilized powder | form solid | form lyophilized powder | form buffered aqueous solution |
| Quality Level 200 | Quality Level 200 | Quality Level 100 | Quality Level 200 |
| storage temp. −20°C | storage temp. −20°C | storage temp. −20°C | storage temp. −70°C |
| Gene Information human ... EDNRA(1909), EDNRB(1910) | Gene Information human ... EDNRB(1910) | Gene Information human ... EDNRA(1909) | Gene Information human ... EDNRA(1909) |
Classe di stoccaggio
11 - Combustible Solids
Che succede?
WGK 3
Punto di infiammabilità (°F)
Not applicable
Punto di infiammabilità (°C)
Not applicable
DPI (dispositivi di protezione individuale)
Eyeshields, Gloves, type N95 (US)
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How should Product B150, BQ-123, be dissolved?
1 answer-
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What is the solution stability for Product B150, BQ-123?
1 answer-
We do not perform any solution stability studies on Product B150, BQ-123. The following reference indicates that the product is stable in solution for 24 hours but no temperature was mentioned. Cardillo, C. et al., Hypertension, 33, 753-758 (1999). The following abstract indicates that BQ-123 was used in an osmotic pump for a 2 week treatment. Bonvollet, S. et al., A.J.P. - Heart, 266 (4), H1327-H1331 (1994).
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What is the Department of Transportation shipping information for this product?
1 answer-
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
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Is Product B150 the free acid form of BQ-123, or is it a salt?
1 answer-
Product No. B150 is BQ123 sodium salt.
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