1.37136

Tetrahydrofuran

EMPROVE^® ESSENTIAL

• Synonyma: Tetrahydrofuran, Butylene oxide, Oxolane, Tetramethylene oxide
• Lineární vzorec: (CH₂)₃CH₂O
• Číslo CAS: 109-99-9
• Molekulová hmotnost: 72.11
• UNSPSC Code: 12352005
• Beilstein/REAXYS Number: 102391
• MDL number: MFCD00005356

Vlastnosti

• Quality Segment: 500
• vapor density: 2.5 (vs air)
• vapor pressure: 114 mmHg ( 15 °C), 143 mmHg ( 20 °C)
• product line: EMPROVE^® ESSENTIAL
• assay: ≥99.8% (GC)
• form: liquid
• autoignition temp.: 610 °F
• expl. lim.: 1.8-11.8 %
• technique(s): API processing | polymorph screening: suitable
• refractive index: n20/D 1.407 (lit.)
• pH: 7-8 (20 °C, 200 g/L in H₂O)
• bp: 65-67 °C (lit.)
• mp: −108 °C (lit.)
• density: 0.889 g/mL at 25 °C (lit.)
• application(s): pharmaceutical
• storage temp.: 2-25°C
• SMILES string: C1CCOC1
• InChI: 1S/C4H8O/c1-2-4-5-3-1/h1-4H2
• InChI key: WYURNTSHIVDZCO-UHFFFAOYSA-N

Popis

General description

We offer a range of high quality critical raw materials, solvents and reagents plus the documentation and expertise to meet stringent regulatory requirements. In addition to our comprehensive portfolio, we also offer custom manufacturing services to meet your exact needs. As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Tetrahydrofuran is a versatile organic solvent for API synthesis, as a pre-cursor to polymers and it is used for several extended applications during drug manufacturing. The performance of the processes increases with the usage of Tetrahydrofuran in certain API′s than other available solvents. Tetrahydrofuran Emprove^® Essential is manufactured according to GMP guidelines and is suitable for pharmaceutical applications.

Other Notes

Emprove Documentation

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Bezpečnostní informace

• Výstražné slovo: Danger
• supp_hazards: EUH019
• Skladovací třída: 3 - Flammable liquids
• Bod vzplanutí (°F): -6.2 °F - closed cup
• Bod vzplanutí (°C): -21.2 °C - closed cup
• Bezpečnostní pokyny: P202 - P210 - P280 - P301 + P312 - P305 + P351 + P338 - P308 + P313
• Cílové orgány: Central nervous system, Respiratory system
• Piktogramy: GHS02,GHS08,GHS05,GHS07
• Kódy nebezpečí: H225,H302,H318,H335,H336,H351
• Hazard Classifications: Acute Tox. 4 Oral - Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - STOT SE 3