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D9170

Dimethyl sulfoxide

PCR Reagent

Synonyma:

DMSO

Přihlásit pro zobrazení organizačních a smluvních cen.

Vybrat velikost

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Vám/SKUDostupnostCena
1 amp
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2 290,00 Kč
5 amp
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8 210,00 Kč

O této položce

Lineární vzorec:
(CH3)2SO
Číslo CAS:
Molekulová hmotnost:
78.13
UNSPSC Code:
12191502
NACRES:
NA.25
PubChem Substance ID:
EC Number:
200-664-3
Beilstein/REAXYS Number:
506008
MDL number:
Assay:
≥99.5%
Technique(s):
PCR: suitable
Bp:
189 °C (lit.)
Vapor pressure:
0.42 mmHg ( 20 °C)

2 290,00 Kč


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Quality Segment

vapor density

2.7 (vs air)

vapor pressure

0.42 mmHg ( 20 °C)

assay

≥99.5%

form

liquid

autoignition temp.

573 °F

shelf life

Recommended retest period - 2 years

expl. lim.

42 %, 63 °F

packaging

vial of 1 mL

technique(s)

PCR: suitable

impurities

≤0.1% water
water

color

colorless

refractive index

n20/D 1.479 (lit.)

bp

189 °C (lit.)

mp

16-19 °C (lit.)

solubility

H2O: miscible (completely)

density

1.10 g/mL (lit.)

suitability

suitable for PCR

application(s)

agriculture

SMILES string

CS(C)=O

InChI

1S/C2H6OS/c1-4(2)3/h1-2H3

InChI key

IAZDPXIOMUYVGZ-UHFFFAOYSA-N

General description

Dimethyl sulfoxide is a free radical scavenger and a cryopreservant. It elicits protective effect in double stranded breaks(DSBs). Dimethyl sulfoxide (1-10%) has been shown to accelerate strand renaturation and is believed to give the nucleic acid thermal stability against depurination. As a PCR cosolvent, DMSO may help improve yields, especially in long PCR.

Application

Dimethyl sulfoxide has been used as a component of polymerase chain reaction (PCR) mixture and as PCR facilitator.

Other Notes

For information on dimethyl sulfoxide miscibility, please visit the following link:
Dimethyl Sulfoxide Miscibility/Immiscibility Table

Disclaimer

Supercools easily and remelts slowly at room temperature. Solidified product can be re-liquified by warming to room temperature without detriment to the product.

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1 of 1

Tato položka
PHR1309317275D2653
description

PCR Reagent

description

Pharmaceutical Secondary Standard; Certified Reference Material

description

ACS Reagent Grade.

description

Hybri-Max™, 0.2 μm filtered, BioReagent, suitable for hybridoma, ≥99.7%, Ampoule

application(s)

agriculture

application(s)

pharmaceutical (small molecule)

application(s)

-

application(s)

-

Quality Level

200

Quality Level

300

Quality Level

100

Quality Level

300

technique(s)

PCR: suitable

technique(s)

gas chromatography (GC): suitable, HPLC: suitable

technique(s)

-

technique(s)

cryopreservation: suitable, cell culture | hybridoma: suitable

assay

≥99.5%

assay

-

assay

≥99% (GC)

assay

≥99.7%

solubility

H2O: miscible (completely)

solubility

-

solubility

-

solubility

H2O: miscible (completely)

form

liquid

form

-

form

liquid

form

liquid


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Skladovací třída

10 - Combustible liquids

Co se děje?

WGK 1

Bod vzplanutí (°F)

188.6 °F - closed cup

Bod vzplanutí (°C)

87 °C - closed cup

PPE (osobní ochranné prostředky)

Eyeshields, Gloves, type ABEK (EN14387) respirator filter



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Osvědčení o analýze (COA)

Lot/Batch Number

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Questions

1–9 of 9 Questions  
  1. How much DMSO is in each of the vials (D9170)?

    1 answer
    1. As stated in the 'PROPERTIES' section, each vial contains 1 mL. One ampule contains 1 mL of Dimethyl Sulfoxide, and 5 amps include 5 ampules containing 1 mL of Dimethyl Sulfoxide. each.

      Helpful?

  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  3. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  4. Where does DMSO come from?

    1 answer
    1. DMSO is known to have been isolated from tree bark in the past. It is now a commericially synthesized solvent.

      Helpful?

  5. What is the molarity of DMSO?

    1 answer
    1. DMSO will have a molarity of 14.1M, based on a density of 1.1 g/mL and a molecular weight of 78.13 g/mol.

      Helpful?

  6. Dimethyl sulfoxide (DMSO) should be a liquid.  Why did it arrive as a solid?

    1 answer
    1. DMSO supercools easily, and re-melts slowly at room temperature. The melting point is 16-19 °C. The solidified product can be re-liquefied by warming to room temperature without detriment to the product.

      Helpful?

  7. What is the DMSO dissolved in?

    1 answer
    1. DMSO is not dissolved in any solvent. It is a pure chemical compound that is a liquid at room temperature.

      Helpful?

  8. What is the Department of Transportation shipping information for this product?

    1 answer
    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

      Helpful?

  9. Does DMSO have any synthetic utility?

    1 answer
    1. DMSO has been used to oxidize thiols and disulfides to sulfonic acids, hydrolysis of epoxides, thioalkylation of phenols, and oxidation of primary alcohols and halides, and esters of primary alcohols to aldehydes.

      Helpful?

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