FD20S
Fluorescein isothiocyanate–dextran
average mol wt 20,000
Synonyma:
FITC–Dextran
Přihlásit pro zobrazení organizačních a smluvních cen.
Vybrat velikost
Změnit zobrazení
| Vám/SKU | Dostupnost | Cena |
|---|---|---|
100 mg | Obraťte se na zákaznický servis a vyžádejte si informaci o dostupnosti. | 4 070,00 Kč |
250 mg | Obraťte se na zákaznický servis a vyžádejte si informaci o dostupnosti. | 8 300,00 Kč |
1 g | Obraťte se na zákaznický servis a vyžádejte si informaci o dostupnosti. | 26 700,00 Kč 20 025,00 Kč |
O této položce
4 070,00 Kč
Obraťte se na zákaznický servis a vyžádejte si informaci o dostupnosti.
Technický servis
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sugar beets root
Quality Segment
conjugate
FITC conjugate
form
powder
mol wt
average mol wt 20,000
extent of labeling
0.003-0.020 mol FITC per mol glucose
color
yellow to dark yellow
solubility
water: 25 mg/mL
storage temp.
2-8°C
General description
Dextran is a polymer of anhydroglucose. It is composed of approximately 95% alpha-D-(166) linkages. The remaining (163) linkages account for the branching of dextran. Conflicting data on the branch lengths implies that the average branch length is less than three glucose units. However, other methods indicate branches of greater than 50 glucose units exist. Native dextran has been found to have a molecular weight (MW) in the range of 9 million to 500 million. Lower MW dextrans will exhibit slightly less branching and have a more narrow range of MW distribution. Dextrans with MW greater than 10,000 behave as if they are highly branched. As the MW increases, dextran molecules attain greater symmetry. Dextrans with MW of 2,000 to 10,000, exhibit the properties of an expandable coil. At MW below 2,000, dextran is more rod-like. The MW of dextran is measured by one or more of the following methods: low angle laser light scattering, size exclusion chromatography, copper-complexation and anthrone reagent colorometric reducing-end sugar determination and viscosity.
Application
FITC-dextran is used in cardiovascular, microcirculation, perfusion, cell monolayer and cell membrane permeability research as fluorescent flux tracer compound that supports the measurement of processes such as blood flow, membrane damage, vascular drainage and renal elimination. Small FITC-dextrans are also used to measure processes such as endocytosis and cell junction permeability. Fluorescein-dextran, 20 kDa, may be used to study cell processes such as endocytosis and osmoporation. FITC-dextran-20 may be used to study endothelial or epithelial monolayer porosity, apical-basolateral movements within cell layers and cell junction permeability. FITC-dextran-20 may be used as a model compound to study drug release from structures such as hydrogens and collagen minirods.
Dextran labeled with fluorescein isothiocyanate for possible use in perfusion studies in animals.
FITC-dextran is used extensively in microcirculation and cell permeability research utilizing microfluorimetry. FITC-dextran has been used to study plant cell wall porosity and capillary permeability. Plasma proteins have been shown not to bind to FITC-dextran.
Preparation Note
Sigma typically tests the solubility of FITC dextrans in water at concentrations at or above 25 mg/ml. Solutions should be protected from light. In vivo, FITC-dextran is stable for more than 24 hours.
Other Notes
Similar to FD-20, but produced by Sigma.
To gain a comprehensive understanding of our extensive range of Dextrans for your research, we encourage you to visit our Carbohydrates Category page.
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Tato položka | |||
|---|---|---|---|
| description average mol wt 20,000 | description average mol wt 250,000 | description average mol wt 20,000 | description average Mw 59,000-77,000 |
| biological source sugar beets root | biological source bacterial (Leuconostoc mesenteroides) | biological source bacterial (Leuconostoc mesenteroides) | biological source bacterial (Leuconostoc mesenteroides) |
| solubility water: 25 mg/mL | solubility water: 25 mg/mL, clear, yellow | solubility water: 25 mg/mL | solubility water: 25 mg/mL |
| Quality Level 200 | Quality Level 200 | Quality Level 100 | Quality Level 100 |
| form powder | form powder | form powder | form powder |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C |
| color yellow to dark yellow | color yellow to orange | color light yellow to dark orange | color light yellow to dark orange |
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Výstražné slovo
Warning
Kódy nebezpečí
Bezpečnostní pokyny
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Cílové orgány
Respiratory system
Skladovací třída
11 - Combustible Solids
Co se děje?
WGK 3
Bod vzplanutí (°F)
Not applicable
Bod vzplanutí (°C)
Not applicable
PPE (osobní ochranné prostředky)
Eyeshields, Gloves, type N95 (US)
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