The solubility of this product has not been determined. Other sources state that this compound may be solubilized in approximately 5 mg/mL of water or 66.67 mg/mL of DMSO. This information has not been validated.
G3923
Gly-Pro-Glu
≥98% (HPLC), NMDA receptor antagonist., powder
Synonyma:
GPE, Glycyl-prolyl-glutamic acid
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| Vám/SKU | Dostupnost | Cena |
|---|---|---|
10 mg | Obraťte se na zákaznický servis a vyžádejte si informaci o dostupnosti. | 2 360,00 Kč |
50 mg | Obraťte se na zákaznický servis a vyžádejte si informaci o dostupnosti. | 9 850,00 Kč |
O této položce
Empirický vzorec (Hillův zápis):
C12H19N3O6
Číslo CAS:
Molekulová hmotnost:
301.30
UNSPSC Code:
12352209
PubChem Substance ID:
NACRES:
NA.32
MDL number:
2 360,00 Kč
Obraťte se na zákaznický servis a vyžádejte si informaci o dostupnosti.
Technický servis
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Dovolte nám, abychom vám pomohliNázev produktu
Gly-Pro-Glu, ≥98% (HPLC)
Quality Segment
assay
≥98% (HPLC)
form
powder
color
white
storage temp.
−20°C
SMILES string
NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(O)=O
InChI
1S/C12H19N3O6/c13-6-9(16)15-5-1-2-8(15)11(19)14-7(12(20)21)3-4-10(17)18/h7-8H,1-6,13H2,(H,14,19)(H,17,18)(H,20,21)/t7-,8-/m0/s1
InChI key
JJGBXTYGTKWGAT-YUMQZZPRSA-N
General description
Biochem/physiol Actions
Gly-Pro-Glu (GPE) is a neuroactive peptide and prevents the binding of glutamate to N-methyl-D-aspartate (NMDA) receptor. It positively regulates the potassium-mediated release of acetylcholine from rat cortical slices. Thus, it is involved in the control of brain function. In vitro studies show that this peptide confers neuroprotection to CA1-2 hippocampal neurons against excitotoxic insult.
Gly-Pro-Glu is a neuroprotective compound and the N-terminal tripeptide of IGF-1.
Gly-Pro-Glu is a neuroprotective compound and the N-terminal tripeptide of IGF-1. Gly-Pro-Glu is neuroprotective after central administration in animal models of neurodegenerative processes, such as Huntington′s, Parkinson′s, Alzheimer′s diseases, and varies acute brain injury animal models. The neuroprotective activity is not related to its affinity to glutamate receptor. Findings indicate that GPE mimics insulin-like growth factor I effects on the somatostatin system through a mechanism independent of β-amyloid clearance that involves modulation of calcium and glycogen synthase kinase 3β signaling.
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Tato položka | |
|---|---|
| description ≥98% (HPLC) | description ≥98% (GC/HPLC) |
| assay ≥98% (HPLC) | assay ≥98% (GC/HPLC) |
| Quality Level 100 | Quality Level 100 |
| form powder | form powder |
| storage temp. −20°C | storage temp. −20°C |
| color white | color - |
Skladovací třída
11 - Combustible Solids
Co se děje?
WGK 3
Bod vzplanutí (°F)
Not applicable
Bod vzplanutí (°C)
Not applicable
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Gly-Pro-Glu(G3923) 10mg 제품 구매하였는데, solubility 를 알고 싶습니다.
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