1021204

4-Aminophenol

United States Pharmacopeia (USP) Reference Standard

• Synonyma: 4-Hydroxyaniline
• Lineární vzorec: H₂NC₆H₄OH
• Číslo CAS: 123-30-8
• Molekulová hmotnost: 109.13
• UNSPSC Code: 41116107
• NACRES: NA.24
• PubChem Substance ID: 329748983
• MDL number: MFCD00007869
• Beilstein/REAXYS Number: 385836

Vlastnosti

• grade: pharmaceutical primary standard
• agency: USP
• API family: paracetamol, acetaminophen, mesalazine
• manufacturer/tradename: USP
• mp: 185-189 °C (lit.)
• application(s): pharmaceutical (small molecule); pharmaceutical
• format: neat
• SMILES string: Nc1ccc(O)cc1
• InChI: 1S/C6H7NO/c7-5-1-3-6(8)4-2-5/h1-4,8H,7H2
• InChI key: PLIKAWJENQZMHA-UHFFFAOYSA-N

Popis

General description

Find answers to frequently asked questions on USP products in USP FAQs.

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets, has been developed and issued under the Authority of the issuing Pharmacopoeia.

For further information and support please go to the website of the issuing Pharmacopoeia.4-Aminophenol is the principal degradation product of acetaminophen, formed as an impurity during its hydrolysis.

Application

This USP reference standard is intended for use in specified quality tests and assays.
Also used to prepare standard and system suitability solutions to test for the presence of 4-aminophenol as an impurity in various pharmaceutical dosage forms of acetaminophen, according to the United States Pharmacopeia (USP) monographs:

• Mesalamine
• Acetaminophen Tablets
• Acetaminophen Oral Suspension
• Tramadol Hydrochloride and Acetaminophen Tablets

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Bezpečnostní informace

• Piktogramy: GHS08,GHS07,GHS09
• Výstražné slovo: Warning
• Kódy nebezpečí: H302 + H332,H317,H341,H373,H410
• Bezpečnostní pokyny: P273 - P280 - P301 + P312 - P302 + P352 - P304 + P340 + P312 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Muta. 2 - Skin Sens. 1 - STOT RE 2
• Cílové orgány: Kidney
• Skladovací třída: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Bod vzplanutí (°F): Not applicable
• Bod vzplanutí (°C): Not applicable