1091108

Capsaicin

United States Pharmacopeia (USP) Reference Standard

• Synonyma: 8-Methyl-N-vanillyl-trans-6-nonenamide
• Lineární vzorec: (CH₃)₂CHCH=CH(CH₂)₄CONHCH₂C₆H₃-4-(OH)-3-(OCH₃)
• Číslo CAS: 404-86-4
• Molekulová hmotnost: 305.41
• UNSPSC Code: 41116107
• NACRES: NA.24
• PubChem Substance ID: 329749225
• MDL number: MFCD00017259
• Beilstein/REAXYS Number: 2816484

Vlastnosti

• grade: pharmaceutical primary standard
• agency: USP
• API family: capsaicin
• manufacturer/tradename: USP
• mp: 62-65 °C (lit.)
• application(s): pharmaceutical (small molecule); pharmaceutical
• format: neat
• storage temp.: 2-8°C
• SMILES string: COc1cc(CNC(=O)CCCC\C=C\C(C)C)ccc1O
• InChI: 1S/C18H27NO3/c1-14(2)8-6-4-5-7-9-18(21)19-13-15-10-11-16(20)17(12-15)22-3/h6,8,10-12,14,20H,4-5,7,9,13H2,1-3H3,(H,19,21)/b8-6+
• InChI key: YKPUWZUDDOIDPM-SOFGYWHQSA-N
• Gene Information: human ... TRPV1(7442)

Popis

General description

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This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Capsaicin USP reference standard for use in specified quality tests and assays.

Also used to prepare standard solutions for the assay, identification, composition and strength analysis according to the given below monographs of United States Pharmacopeia (USP):

• Capsaicin
• Capsicum Oleoresin
• Capsicum
• Ginger Tincture

Biochem/physiol Actions

Prototype vanilloid receptor agonist. Neurotoxin; activates sensory neurons that give rise to unmyelinated C-fibers, many of which contain substance P. Topical application desensitizes the sensory nerve endings giving a paradoxical antinociceptive effect; systemic administration can be neurotoxic to capsaicin-sensitive cells, especially in newborn animals. Active component of chili peppers.

Prototype vanilloid receptor agonist; neurotoxin. Active component of chili peppers.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Bezpečnostní informace

• Piktogramy: GHS06,GHS08,GHS05
• Výstražné slovo: Danger
• Kódy nebezpečí: H300,H315,H317,H318,H334,H335
• Hazard Classifications: Acute Tox. 2 Oral - Eye Dam. 1 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
• Cílové orgány: Respiratory system
• Skladovací třída: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• Bod vzplanutí (°F): 235.4 °F - closed cup
• Bod vzplanutí (°C): 113 °C - closed cup
• Bezpečnostní pokyny: P261 - P264 - P280 - P301 + P310 - P302 + P352 - P305 + P351 + P338