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EHU059261

MISSION® esiRNA

targeting human TFEB

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CZK 5,620.00

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CZK 9,990.00

CZK 5,620.00

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About This Item

NACRES:
NA.51
UNSPSC Code:
41105324

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Product Name

MISSION® esiRNA, targeting human TFEB

description

Powered by Eupheria Biotech

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

GCGGCAGAAGAAAGACAATCACAACTTAATTGAAAGGAGACGAAGGTTCAACATCAATGACCGCATCAAGGAGTTGGGAATGCTGATCCCCAAGGCCAATGACCTGGACGTGCGCTGGAACAAGGGCACCATCCTCAAGGCCTCTGTGGATTACATCCGGAGGATGCAGAAGGACCTGCAAAAGTCCAGGGAGCTGGAGAACCACTCTCGCCGCCTGGAGATGACCAACAAGCAGCTCTGGCTCCGTATCCAGGAGCTGGAGATGCAGGCTCGAGTGCACGGCCTCCCTACCACCTCCCCGTCCGGCATGAACATGGCTGAGCTGGCCCAGCAGGTGGTGAAGCAGGAGCTGCCTAGCGAAGAGGGCCCAGGGGAGGCCCTGATGCTGGGGGCTGAGGTCCCTGACCCTGAGCCACTGCCAGCTCTGCCCCCGCAAGCCCCGCTGCCCCTGCCCACCCAGCCACCATCCCCATTCCATCACCTGGACTTCAGCCAC

Ensembl | human accession no.

ENSG00000112561

NCBI accession no.

NM_007162

shipped in

ambient

storage temp.

−20°C

Quality Level

100

Gene Information

human ... TFEB(7942), TFEB(7942)

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This Item
EHU035761EHU078581EHU094271
MISSION® esiRNA targeting human TFEB

Sigma-Aldrich

EHU059261

MISSION® esiRNA

MISSION® esiRNA targeting human TSEN34

Sigma-Aldrich

EHU035761

MISSION® esiRNA

MISSION® esiRNA targeting human UBP1

Sigma-Aldrich

EHU078581

MISSION® esiRNA

MISSION® esiRNA targeting human ST7

Sigma-Aldrich

EHU094271

MISSION® esiRNA

Ensembl | human accession no.

ENSG00000112561

Ensembl | human accession no.

ENSG00000170892

Ensembl | human accession no.

ENSG00000153560

Ensembl | human accession no.

ENSG00000004866

product line

MISSION®

product line

MISSION®

product line

MISSION®

product line

MISSION®

esiRNA cDNA target sequence

GCGGCAGAAGAAAGACAATCACAACTTAATTGAAAGGAGACGAAGGTTCAACATCAATGACCGCATCAAGGAGTTGGGAATGCTGATCCCCAAGGCCAATGACCTGGACGTGCGCTGGAACAAGGGCACCATCCTCAAGGCCTCTGTGGATTACATCCGGAGGATGCAGAAGGACCTGCAAAAGTCCAGGGAGCTGGAGAACCACTCTCGCCGCCTGGAGATGACCAACAAGCAGCTCTGGCTCCGTATCCAGGAGCTGGAGATGCAGGCTCGAGTGCACGGCCTCCCTACCACCTCCCCGTCCGGCATGAACATGGCTGAGCTGGCCCAGCAGGTGGTGAAGCAGGAGCTGCCTAGCGAAGAGGGCCCAGGGGAGGCCCTGATGCTGGGGGCTGAGGTCCCTGACCCTGAGCCACTGCCAGCTCTGCCCCCGCAAGCCCCGCTGCCCCTGCCCACCCAGCCACCATCCCCATTCCATCACCTGGACTTCAGCCAC

esiRNA cDNA target sequence

AGCGAGGCTTCTTCCTCAGTGCGGCTGGCAAGTTCGGAGGTGACTTCCTGGTCTATCCTGGTGACCCCCTCCGCTTCCACGCCCATTATATCGCTCAGTGCTGGGCCCCCGAGGACACCCACTCCAAGACCTGGTTGCTGCTGGGCGCCTTGGAACCAGCGTCAGAAAGACCCTGCTCCTCTGTTCTCCGCAGCCTGATGGTAAGGTGGTCTACACCTCCCTGCAATGGGCCAGCCTGCAGTGAACTCCAGAGACCTAGGGGATGTGGCTGTGTCGGCAGCAAGAGCCTTTCTGGATGTTCCCCAGCTCTTCTCTGGGAGTCTAGAACATCCTCCTACCTTTCTCCGCGGTTAGTTTTTGATTCCAGGTTTTCGAACACTACATCTTTTTTATGTTCTTCCTTGTTTCAAAGCACTTATTGGCTGTGTTTTTGTAGTTACCTATTTTCACACTGTGAGCTTCCCGAGAATG

esiRNA cDNA target sequence

CCATAGCCAAGCATCCTCATGAGAGTGAGCACATCGGCACAGCATGCATCCAGCTCTGGAGGCCACGGTGCAGGCATAGCTGCCTGCTGCTCTGGCAGAGGCCAGTAAATACAGTTCCTAGAAGCAGCCTTTGCTGTCTTTTTACACTGTATGCGGTTTGGAAATGAATGTAGAAACTTACTGTGGGCATTTACCTTTCTGTGCCAGTTTGGCTTTTATTGCCTGAACCTTATGCTGACCTGGAGAGGAGATGGGGGACAGTGCTGTTGTGGGGCCAGCAGTGAATCTGTATGCGGAGAGTTGTGTTGTGCTGATGTGGCCGTTGGTGGTCAGGTAAGAGGCTCGGCACCTTCTTGGAAGAAATCATGTCTGAGGGTGTACGTTTGATATGATCATGCCAGATTGGAGAAGATCCAAGCCAGGAAGATGGGCTTGAAGCAAA

esiRNA cDNA target sequence

CAACCATTGCTGAAGCAGAAAAATTATTTAAGCAGGCCCTGAAGGCTGGAGATGGCTGTTACCGACGCTCTCAGCAGCTACAACATCATGGATCCCAGTATGAAGCCCAACATAGACGAGACACCAATGTCTTGGTGTACATCAAAAGAAGGCTAGCAATGTGTGCCAGAAGACTCGGGAGGACCAGGGAAGCAGTGAAAATGATGAGAGATTTAATGAAGGAGTTCCCCCTTCTGAGTATGTTCAATATCCATGAAAACCTTTTAGAAGCCCTTCTGGAACTACAAGCATATGCTGATGTTCAGGCAGTCTTAGCAAAGTATGATGATATAAGCTTACCAAAGTCAGCAACAATATGCTACACAGCTGCTTTGCTCAAAGCAAGAGCTGTCTCTGACAAATTCTCTCCTGAGGCTGCATCT

Gene Information

human ... TFEB(7942), TFEB(7942)

Gene Information

human ... TSEN34(79042), TSEN34(79042)

Gene Information

human ... UBP1(7342), UBP1(7342)

Gene Information

human ... ST7(7982), ST7(7982)

form

lyophilized powder

form

lyophilized powder

form

lyophilized powder

form

lyophilized powder

NCBI accession no.

NM_007162

NCBI accession no.

NM_001077446

NCBI accession no.

NM_014517

NCBI accession no.

NM_021908

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

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Sijie Tan et al.
Scientific reports, 9(1), 727-727 (2019-01-27)
Mitochondrial dysfunction underscores aging and diseases. Mitophagy (mitochondria + autophagy) is a quality control pathway that preserves mitochondrial health by targeting damaged mitochondria for autophagic degradation. Hence, molecules or compounds that can augment mitophagy are therapeutic candidates to mitigate mitochondrial-related diseases. However
Muzo Wu et al.
American journal of physiology. Lung cellular and molecular physiology, 313(1), L138-L153 (2017-04-15)
Downregulation of the alveolar macrophage (AM) receptor with collagenous structure (MARCO) leads to susceptibility to postinfluenza bacterial pneumonia, a major cause of morbidity and mortality. We sought to determine whether immunomodulation of MARCO could improve host defense and resistance to
Li He et al.
Journal of leukocyte biology, 100(5), 1113-1124 (2016-11-02)
Macrophage dysfunction in obesity and diabetes is associated with persistent inflammation and poor wound healing responses. Relevant to these phenotypes, we have previously shown that macrophage activation in a high-fat environment results in cell death via a mechanism that involves
Xingchen Zhao et al.
The Journal of pathology, 245(2), 235-248 (2018-03-24)
Insufficient autophagy in podocytes is related to podocyte injury in diabetic nephropathy (DN). Advanced glycation end-products (AGEs) are major factors of podocyte injury in DN. However, the role and mechanism of AGEs in autophagic dysfunction remain unknown. We investigated autophagic
Hong-Ying Chu et al.
Cancer letters, 423, 105-112 (2018-03-11)
The role of autophagy in tongue squamous cell carcinoma (TSCC) cisplatin resistance is unclear. We aimed to identify a possible synergistic effect of autophagy inhibitors and cisplatin in TSCC cells and explore the underlying mechanism. Our results indicate that autophagic
View All Related Papers

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