Skip to Content
Merck

OLIGO

Custom DNA Oligos

Design and Order Custom Oligos

Synonym(s):

Custom DNA Oligos, DNA, DNA primer, High-throughput DNA, ISO 13485 Oligos, Locked Nucleic Acid oligos, Modified oligos, NGS adapters, NGS−grade oligos, Next−generation sequencing adapters, Next−generation sequencing oligos, Oligonucleotide, Oligonucleotides, Oligos, Oligos in plates, cGMP Oligos

Sign In to View Organizational & Contract Pricing

About This Item

UNSPSC Code:
41105327

Skip To

Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

      


Standard DNA Oligos

  • Scale: 0.025, 0.05, 0.2, 1.0, 10, and 15 μmol
  • Purification: Desalt, Cartridge, HPLC, and PAGE
  • Sequence Length: Up to 120 bases
  • Modifications: Over 200 available, including dyes (fluorescent and non-fluorescent)
  • Quality Control: 100% Mass Spectrometry
  • Format: Supplied dry or in solution – tubes, plates and mixed plates (forward and reverse primers)
  • WellRED Oligos: Available
  • qPCR Probes: Available
  • Learn more about Standard DNA Synthesis

Tubes

Plates


Easy Oligo

  • Amount: 3 OD
  • Concentration: 100 µM
  • Purification: Desalt
  • Sequence Length: 15 - 30 bases
  • Modifications: Not available
  • Quality Control: 100% Mass Spectrometry
  • Format: Supplied in solution
  • Ships within 24 hours of order receipt
  • Learn more

Tubes


Pure & Simple Primers

  • Amount: 3 OD
  • Purification: Cartridge
  • Sequence Length: 12 - 35 bases
  • Modifications: Not available
  • Quality Control: 100% Mass Spectrometry
  • Format: Supplied dry
  • Ships within 24 hours of order receipt
  • Learn more

Tubes


iScale Oligos™ (mg & g quantity)

  • Larger quantities for in vivo, high throughput and commercial projects
  • Quantity: 10, 25, 50, 100, 250, 500 mg; 1, 2, 5, 10, 15 g
  • Purification: Desalt, RP-HPLC & In vivo treatment
  • Sequence Length: 10 - 55 bases (Inquire for longer lengths)
  • Modifications: 6-FAM, Biotin, Phosphate, Amino-Modifiers & others
  • Quality Control: 100% Mass Spectrometry
  • Format: Supplied dry
  • Services: Salt Exchange, Filtration & Endotoxin Testing
  • Learn more

Tubes


Next-Gen Sequencing Oligos

  • Custom universal and index (barcode) adapter oligos for major sequencing platforms
  • Suitable purity (percent full-length sequence) to maintain sequence read integrity
  • Low levels of cross-contamination to facilitate proper sequence assembly
  • Learn more

Commercial Oligos

  • Custom DNA Primers, qPCR Probes, and Next-Gen Sequencing Oligos for Life Science Research Tools, Molecular Diagnostics (MDx), and Laboratory Developed Tests (LDTs)
  • Component or complete kit manufacturing, including custom formulations, packaging, and private labeling
  • Learn more

GMP OLIGOS

  • Custom cGMP Oligos, available with custom specifications, are Commercial Oligos (raw materials) for MDx and LDTs
  • Learn more

Locked Nucleic Acid

  • Available with Custom DNA Oligos
  • Increased thermal stability and hybridization specificity
  • Easier and more specific designs for problematic target sequences
  • Learn more

Tubes

Sign In To Continue

To continue reading please sign in or create an account.

Don't Have An Account?
Fuqiang Chen et al.
Nature methods, 8(9), 753-755 (2011-07-19)
Zinc-finger nucleases (ZFNs) have enabled highly efficient gene targeting in multiple cell types and organisms. Here we describe methods for using simple ssDNA oligonucleotides in tandem with ZFNs to efficiently produce human cell lines with three distinct genetic outcomes: (i)
T N Wiegner et al.
Marine pollution bulletin, 114(2), 952-961 (2016-11-22)
Spatial and temporal patterns of coastal microbial pollution are not well documented. Our study examined these patterns through measurements of fecal indicator bacteria (FIB), nutrients, and physiochemical parameters in Hilo Bay, Hawai'i, during high and low river flow. >40% of
Leonel Armas-López et al.
Oncotarget, 8(40), 67056-67081 (2017-10-06)
Several homeobox-related gene (HOX) transcription factors such as mesenchyme HOX-2 (MEOX2) have previously been associated with cancer drug resistance, malignant progression and/or clinical prognostic responses in lung cancer patients; however, the mechanisms involved in these responses have yet to be
Eun Jung Thak et al.
Journal of microbiology (Seoul, Korea), 56(1), 11-23 (2018-01-05)
Protein glycosylation, the most universal and diverse post-translational modification, can affect protein secretion, stability, and immunogenicity. The structures of glycans attached to proteins are quite diverse among different organisms and even within yeast species. In yeast, protein glycosylation plays key
Chong He et al.
PLoS genetics, 10(12), e1004860-e1004860 (2014-12-19)
The common non-steroidal anti-inflammatory drug ibuprofen has been associated with a reduced risk of some age-related pathologies. However, a general pro-longevity role for ibuprofen and its mechanistic basis remains unclear. Here we show that ibuprofen increased the lifespan of Saccharomyces

Articles

Techniques for long oligo synthesis and purification offer superior quality unmatched by other suppliers.

Learn about the importance of oligonucleotide purification, recommended methods, common techniques and applications, and key steps in the processes.

Rosetta siRNA Design Algorithm optimizes siRNA sequences for reduced off-target effects and increased RNAi performance.

Regardless of next-generation sequencing (NGS) platform, universal and index adapter sequences are required for the proper assembly of sample fragments.

See All

Related Content

Use our synthetic, small interfering RNA (siRNA) duplex plates to identify gene function, elucidate pathways, and screen for potential new drug targets.

RNA interference via siRNA offers precise gene silencing, aiding gene function studies and drug target screening.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service