A5144

8-Anilino-1-naphthalenesulfonic acid hemimagnesium salt hydrate

Name: 8-Anilino-1-naphthalenesulfonic acid hemimagnesium salt hydrate
Brand: SIAL

≥95% purity (perchloric acid titration), for fluorescence, powder

Sinónimos:

1,8-ANS magnesium salt, ANSA magnesium salt, Magnesium 8-anilino-1-naphthalenesulfonate hydrate, N-Phenyl peri acid magnesium salt

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Fórmula empírica (notación de Hill):

C₁₆H₁₂Mg_0.5NO₃S · xH₂O

Número CAS:

18108-68-4

Peso molecular:

310.49 (anhydrous basis)

NACRES:

NA.47

PubChem Substance ID:

329770870

UNSPSC Code:

12171500

EC Number:

242-004-7

MDL number:

MFCD16661224

Beilstein/REAXYS Number:

4834623

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Nombre del producto

8-Anilino-1-naphthalenesulfonic acid hemimagnesium salt hydrate, suitable for fluorescence, ≥95% (TLC)

InChI key

FBANPIUXAXTAFX-UHFFFAOYSA-L

InChI

1S/2C16H13NO3S.Mg.H2O/c2*18-21(19,20)15-11-5-7-12-6-4-10-14(16(12)15)17-13-8-2-1-3-9-13;;/h2*1-11,17H,(H,18,19,20);;1H2/q;;+2;/p-2

SMILES string

O.[Mg++].[O-]S(=O)(=O)c1cccc2cccc(Nc3ccccc3)c12.[O-]S(=O)(=O)c4cccc5cccc(Nc6ccccc6)c45

assay

≥95% (TLC)

form

powder

color

faint green to green

solubility

H₂O: 50 mg/mL

suitability

suitable for fluorescence

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

Quality Level

200

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Este artículo	10419	A1028	10417
Sigma-Aldrich A5144 8-Anilino-1-naphthalenesulfonic acid hemimagnesium salt hydrate	Sigma-Aldrich 10419 8-Anilino-1-naphthalenesulfonic acid hemimagnesium salt hydrate	Sigma-Aldrich A1028 8-Anilino-1-naphthalenesulfonic acid	Sigma-Aldrich 10417 8-Anilino-1-naphthalenesulfonic acid ammonium salt
grade for fluorescence	grade for fluorescence	grade -	grade for fluorescence
color faint green to green	color -	color black, gray to dark green	color -
application(s) diagnostic assay manufacturing hematology histology	application(s) diagnostic assay manufacturing hematology histology	application(s) diagnostic assay manufacturing hematology histology	application(s) -
form powder	form powder	form powder	form solid
solubility H₂O: 50 mg/mL	solubility hot water: 50 mg/mL, green	solubility DMF: 50 mg/mL	solubility H₂O: 0.1 g/5mL, clear to very slightly hazy (hot), NaOH: 1 N, H₂O: soluble, acetone: soluble, methanol: soluble
storage temp. room temp	storage temp. room temp	storage temp. room temp	storage temp. -

General description

ANSA (8-Anilino-1-naphthalenesulfonic acid) is a hydrophobic polarity sensitive fluorescent dye useful as a site probe to detect conformational changes in cell and micelle membranes and molecules such as proteins. ANSA is also used as a fluorescent probe for the estimation of the critical micelle concentration (CMC) of surfactants.

pictograms

GHS07

signalword

Warning

hcodes

H315,H319,H335

pcodes

P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Shilpi Gupta et al.

Small (Weinheim an der Bergstrasse, Germany), 9(6), 894-904 (2012-12-12)

A new class of non-ionic dendronized multiamphiphilic polymers is prepared from a biodegradable (AB)n-type diblock polymer synthesized from 2-azido-1,3-propanediol (azido glycerol) and polyethylene glycol (PEG)-600 diethylester using Novozym-435 (Candida antarctica lipase) as a biocatalyst, following a well-established biocatalytic route. These

pH-Induced molten globule state of Rhizopus niveus lipase is more resistant against thermal and chemical denaturation than its native state.

Gulam Rabbani et al.

Cell biochemistry and biophysics, 62(3), 487-499 (2012-01-05)

Here, we have characterized four pH-dependent states: alkaline state, "B" (pH 9.0), native state, "N" (pH 7.4), acid-induced state, "A" (pH 2.2) and molten globule state, "MG" (pH 1.8) of Rhizopus niveus lipase (RNL) by CD, tryptophanyl fluorescence, ANS binding

Combined biophysical and cell-based approaches for the assessment of ligand binding to PPARγ.

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Methods in molecular biology (Clifton, N.J.), 952, 237-252 (2012-10-27)

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Kinetics and thermodynamics of 1-anilino-8-naphthalene sulfonate interactions with Urinary Trypsin Inhibitor.

Zhenyu Zuo et al.

The protein journal, 31(7), 585-591 (2012-08-10)

The interactions between Urinary Trypsin Inhibitor (UTI) and 1-anilino-8-naphthalene sulfonate (ANS) were investigated by fluorescence spectra, isothermal titration calorimetry and molecular modeling. The results revealed the presence of four specific binding sites for ANS on UTI, with interactions driven mainly

Opposing effects of Na+ and K+ on the thermal stability of Na+,K(+)-ATPase.

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The journal of physical chemistry. B, 116(10), 3421-3429 (2012-01-31)

Folding and structural stability are key factors for the proper biological function of proteins. Na(+),K(+)-ATPase is an integral membrane protein involved in the active transport of Na(+) and K(+) across the plasma membrane. In this work we characterized the effects

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