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Merck

P1037

Fenol

Molecular Biology

Sinónimos:

Hidroxibenceno

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Fórmula lineal:
C6H5OH
Número CAS:
Peso molecular:
94.11
UNSPSC Code:
12352104
NACRES:
NA.31
PubChem Substance ID:
EC Number:
203-632-7
Beilstein/REAXYS Number:
969616
MDL number:
Grade:
Molecular Biology
Assay:
≥99.0% (GC)
Bp:
182 °C (lit.)
Vapor pressure:
0.09 psi ( 55 °C)
0.36 mmHg ( 20 °C)

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Nombre del producto

Fenol, Molecular Biology

InChI key

ISWSIDIOOBJBQZ-UHFFFAOYSA-N

InChI

1S/C6H6O/c7-6-4-2-1-3-5-6/h1-5,7H

SMILES string

Oc1ccccc1

grade

Molecular Biology

vapor density

3.24 (vs air)

vapor pressure

0.09 psi ( 55 °C)
0.36 mmHg ( 20 °C)

assay

≥99.0% (GC)

form

crystals

autoignition temp.

1319 °F

does not contain

preservative

expl. lim.

8.6 %

impurities

≤2 ppm Mg
≤5 ppm Pb

color

white to off-white

bp

182 °C (lit.)

mp

40-42 °C (lit.)

density

1.071 g/mL at 25 °C (lit.)

suitability

suitable for molecular biology

storage temp.

2-8°C

Quality Level

Gene Information

human ... GABRA1(2554)

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1 of 4

Este artículo
776073281118.22296
assay

≥99.0% (GC)

assay

~73% (T)

assay

≥99%

assay

≥99% (GC)

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

200

grade

for molecular biology

grade

for molecular biology

grade

-

grade

-

form

crystals

form

liquid

form

crystalline (solid), crystals, liquid (after melt)

form

crystalline solid

density

1.071 g/mL at 25 °C (lit.)

density

1.071 g/mL at 25 °C (lit.)

density

1.071 g/mL at 25 °C (lit.)

density

1.071 g/mL at 25 °C (lit.)

impurities

≤2 ppm Mg, ≤5 ppm Pb

impurities

DNases, none detected, RNases, none detected, insoluble matter, passes filter test, phosphatases, none detected, proteases, none detected

impurities

-

impurities

-

Application

Phenol has been used:
  • in solid-phase peptide synthesis[1]
  • as a component of DNA extraction buffer[2]
  • as a component of Alexander′s stain solution[3]

Biochem/physiol Actions

Phenol is majorly used in cosmetics and pharmaceuticals.[4] Phenol pollutes water bodies and inhibits the γ-aminobutyric acid receptor (GABAAR)-coupled chloride ATPase function in the fish brain.[5]

Packaging

Redistilled and packaged under nitrogen in amber bottles.

Comparable product

Referencia del producto
Descripción
Precios

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Muta. 2 - Skin Corr. 1B - STOT RE 2

target_organs

Nervous system,Kidney,Liver,Skin

Clase de almacenamiento

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 2

flash_point_f

177.8 °F - closed cup

flash_point_c

81 °C - closed cup


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Effect of phenol on the GABAAR-coupled Cl-/HCO3-ATPase from fish brain: An in vitro approach on the enzyme function
Menzikov SA
Toxicology in vitro, 46(1), 129-136 (2018)
Single prokaryotic cell isolation and total transcript amplification protocol for transcriptomic analysis.
Kang Y, et al.
Nature Protocols, 10(7), 974-974 (2015)
Rapid separation of Arabidopsis male gametophyte developmental stages using a Percoll gradient
Duplakova N, et al.
Nature Protocols, 11(10), 1817-1817 (2016)
Comparative QSAR evidence for a free-radical mechanism of phenol-induced toxicity
Hansch C, et al.
Chemico-Biological Interactions, 127(1), 61-72 (2000)
Zhibo Liu et al.
Nature protocols, 10(9), 1423-1432 (2015-08-28)
Herein we present a general protocol for the functionalization of biomolecules with an organotrifluoroborate moiety so that they can be radiolabeled with aqueous (18)F fluoride ((18)F(-)) and used for positron emission tomography (PET) imaging. Among the β(+)-emitting radionuclides, fluorine-18 ((18)F)

Preguntas

1–3 de 3 Preguntas  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 respuesta
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      ¿Le ha resultado útil?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 respuesta
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      ¿Le ha resultado útil?

  3. Hi, I would like to buy a Water-saturated phenol with pH around 4. Can you send me a link for exactly this product, please? Thanks a lot!

    1 respuesta
    1. Water-saturated phenol is available in two product options. Product P9346 (Liquified Phenol) and Product 843984 (Phenol, 90% solution in water). Both options are approximately 90 percent phenol and 10 percent water by weight. Water-saturated phenol typically has a pH of approximately 4; however, pH is not one of the Quality Control specifications for either product. Please see the links below to review each of these product options:
      P9346
      https://www.sigmaaldrich.com/product/sial/p9346

      842983
      https://www.sigmaaldrich.com/product/mm/843984

      Note that this does not refer to a buffer-equilibrated phenol... these products are simply water plus phenol.

      ¿Le ha resultado útil?

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