Merck
Todas las fotos(2)

G5146

Sigma-Aldrich

D-(+)-Glucose

Hybri-Max, powder, BioReagent, suitable for hybridoma

Sinónimos:
Dextrose
Empirical Formula (Hill Notation):
C6H12O6
Número de CAS:
Peso molecular:
180.16
Beilstein:
1724615
Número de EC:
Número MDL:
ID de la sustancia en PubChem:
NACRES:
NA.75

origen biológico

maize

grado

Hybri-Max

línea de producto

BioReagent

ensayo

≥99.5%

formulario

powder

technique(s)

cell culture | hybridoma: suitable

impurezas

endotoxin, tested

mp

150-152 °C (lit.)

solubilidad

H2O: 2g + 15 mL, clear, colorless

SMILES string

OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6+/m1/s1

InChI key

WQZGKKKJIJFFOK-DVKNGEFBSA-N

Gene Information

human ... PYGM(5837)

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Descripción general

Glycogen phosphorylase (PYG) exists as brain and muscle isoform. It is expressed in astrocytes and neurons respectively. The PYGM gene is mapped to human chromosome 11q13.1.

Aplicación

D-(+)-Glucose has been used in cell engineering. It has also been used to perform oral glucose tolerance test.

Envase

1 kg in poly bottle
10 kg in poly drum

Acciones bioquímicas o fisiológicas

Glycogen phosphorylase, muscle associated (PYGM), is an important contributor to glycogenolysis. Down regulation of PYGM gene is observed in schizophrenia. Mutation in PYGM leads to McArdle disease, a glycogen storage disorder. The PYGM gene is significantly associated with energy production.

Información legal

Hybri-Max is a trademark of Sigma-Aldrich Co. LLC

Código de clase de almacenamiento

11 - Combustible Solids

WGK

WGK 1

Equipo de protección personal

Eyeshields, Gloves, type N95 (US)

Certificado de Análisis

Introduzca el número de lote para buscar un certificado de análisis (COA).

Certificado de origen

Introduzca el número de lote para buscar un Certificado de origen (COO).

Genetic evaluation of AMPD1, CPT2, and PGYM metabolic enzymes in patients with chronic fatigue syndrome
Maltese PE, et al.
Genetics and molecular research : GMR, 15(3), 1-10 (2016)
Novel variant in the PYGM gene causing late-onset limb-girdle myopathy, ptosis, and camptocormia
Cheraud C, et al.
Muscle and Nerve, 57(1), 157-160 (2018)
CDKN1C/p57 kip2 is a candidate tumor suppressor gene in human breast cancer
Larson PS, et al.
BMC Cancer, 8(1), 68-68 (2008)
Electrical vs manual acupuncture stimulation in a rat model of polycystic ovary syndrome: different effects on muscle and fat tissue insulin signaling
Johansson J, et al.
PLoS ONE, 8(1) (2013)
Comparative metabolic analysis of CHO cell clones obtained through cell engineering, for IgG productivity, growth and cell longevity
Wilkens CA and Gerdtzen ZP
PLoS ONE, 10(3) (2015)

Artículos

Aerobic Glycolysis and the Warburg Effect

We presents an article about the Warburg effect, and how it is the enhanced conversion of glucose to lactate observed in tumor cells, even in the presence of normal levels of oxygen. Otto Heinrich Warburg demonstrated in 1924 that cancer cells show an increased dependence on glycolysis to meet their energy needs, regardless of whether they were well-oxygenated or not.

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